Giant Solitary Trichoepithelioma: A Case Report

Abstract

Giant solitary trichoepithelioma (GST) is a rare adnexal skin tumor with hair structure differentiation. It varies from trichoepithelioma in size (>2cm) and location (common in thigh and perianal region). So far only 18 cases of GST have been reported worldwide. This is a case of GST in the thigh of a 42 year old man. This form of trichoepithelioma can be a cellular tumor which needs to be differentiated from trichoblastoma, keratotic basal cell carcinoma, nevoid basal cell carcinoma and microcystic adnexal carcinoma.

Giant solitary trichoepithelioma: A rare trichogenic tumor

“…Trichoepithelioma was first described by Brook in 1892 as "Epithelioma Adenoides Cysticum",so it is also known as Brooke's tumor. 2 It is a hamartoma of hair germ cells and genodermatosis. 6 Giant solitary trichoepithelioma is a rare form of solitary Trichoepithelioma measuring more than 2 cm in diameter.…”

“…1 Most of the adnexal tumors are of dermal or subcutaneous origin but epidermal connection has also been seen in some cases. 2 Different variants of trichoepithelioma include: Multiple Trichoepithelioma, Solitary, Giant solitary and Desmoplastic; out of which multiple trichoepitheliomas are most common. Histopathologically, these are divided into basaloid, clear or eosinophilic and tumors with glandular differentiation; although histopathologically all variants are similar but not identical.…”