Giant retroperitoneal liposarcoma: Case report and review of the literature

Abstract

HighlightsThe origin from perirenal fat is very uncommon.The occurrence of hematogenous metastasis is a rare finding at the time of diagnosis.The undifferentiated and pleomorphic type are neoplasm with high grade of malignancy.In case of diagnostic doubt and in presence of recurrence, magnetic resonance imaging (MRI) may be useful because can identifying in a reliable manner the satellite localizations of the main lesion.The complete surgical (R0) resection represents the only possibility of radical treatment.Following surgical resection, the 50–100% of liposarcomas recur from residual tissue, which is the primary cause of death.Percutaneous biopsy has low accuracy in the diagnosis of retroperitoneal dedifferentiated liposarcoma (DDLS).

Successful treatment of advanced pancreatic liposarcoma with apatinib: A case report and literature review

“…11,12,13 Specifically, Carefully performed CT or magnetic resonance imaging (MRI) can be pathognomonic for well-and dedifferentiated liposarcoma and in many cases can be highly suggestive of histologic diagnosis. 14,15 Although liposarcoma is the most common retroperitoneal soft tissue tumor, it still has some difficulties pertaining to diagnosis and treatment, 16 because of its concealed location combined with its unconspicuous incipient symptom. Therefore, aggressive surgical resection had indeed provided a productive opportunity for curing the local lesions.…”

A Case Demonstrating the Diagnostic and Surgical Difficulties of a Primary Dedifferentiated Retroperitoneal Liposarcoma

“…On CT and MR imaging, WDL appears similar to adipose tissue and tends to be well encapsulated. In contrast, DL typically demonstrates a nonlipomatous heterogenous mass [5]. There is a local recurrence rate of about 40% for DL, with 28% passing away because of the malignancy [2].…”

Huge retroperitoneal liposarcoma with renal involvement requires nephrectomy: A case report and literature review

“…Such tumors are often identified using a diagnostic modality, including computed tomography or magnetic resonance imaging. R0 resection of retroperitoneal liposarcoma had been suggested as the only way to cure the patients (2,8,10).…”

“…Although the incidence rate is very low, early diagnosis is often difficult since symptoms appear only when the tumor becomes very large. Retroperitoneal liposarcoma is classified into five subtypes, according to the World Health Organization Classification: i) Well-differentiated; ii) dedifferentiated; iii) myxoid cell; iv) pleomorphic; v) mixed-type (2). The kidney is the most frequently invaded organ.…”