Giant Retroperitoneal Liposarcoma: A Case Report

Abstract

Soft tissue sarcomas represent less than 1% of all human neoplasms. One-third of malignant tumors that arise in the retroperitoneum are sarcomas and liposarcoma is the most common retroperitoneal sarcoma. More often than not, patients report late to the hospital due to the slow progress and few late symptoms. Thus, the tumor is known to grow to enormous sizes. Here, we report a case of giant retroperitoneal liposarcoma weighing more than 7 kgs.

A Giant Retroperitoneal Liposarcoma Encasing the Entire Left Kidney and Adherent to Adjacent Structures: A Case Report

“…Between 10 and 15% of soft tissue sarcomas originate within the retroperitoneal space, and the most common type among these is liposarcoma [ 3 ]. However, liposarcoma is very rare overall, accounting for 0.2–0.3% of all malignancies [ 2 ].…”

“…Among those subtypes, liposarcoma is one of the most common soft tissue sarcomas [ 1 ]. Furthermore, among sarcomas originating within the retroperitoneum, which constitute 10–15% of all soft tissue sarcomas, liposarcomas are the most common histologic type, accounting for 41% of these tumors [ 2 , 3 ]. Liposarcomas are generally located in the head, neck, trunk, mediastinum, upper and lower extremities, gastrointestinal tract, and retroperitoneum [ 4 ].…”

Retro-Peritoneal Liposarcoma: Diagnostic Difficulties and Therapeutic Attitudes

“…It's the single most common soft tissue sarcoma which corresponds to 10-14% of all them [2,3] and the most common retroperitoneal sarcoma [2]. Histologically, they are subdivided into four subgroups based on morphology and cytogenic abnormalities: well differentiated (WDL), dedifferentiated (DDL), myxoid/round cell, and pleomorphic [4][5][6][7]. This tumor raises several diagnostic and therapeutic problems.…”

Coincident retroperitoneal and sigmoid colon liposarcoma: A rare occurrence

“…Soft tissue sarcomas are less than 1% among all types of cancer [1]. One-third of malignant tumors originating from retroperitoneum are sarcomas and liposarcomas are the most frequently observed retroperitoneal sarcoma types [2].…”

“…There is no known etiological factor in the pathogenesis of liposarcomas yet. There are five types of liposarcomas: well differentiated, myxoid, round cell, pleomorphic, and undifferentiated, out of these types pleomorphic and undifferentiated types have poorer prognosis due to high recurrence and metastasis rates [1,4].…”