Giant primary liposarcoma of the chest

Abstract

Liposarcomas are the most common soft tissue sarcomas in adults, although liposarcomas of the chest are uncommon. We report two cases of giant liposarcoma in the mediastinum and chest wall, respectively. An 82-year-old man presented with a mass in the right upper mediastinum, as seen by computed tomography (CT). He had a past history of subcutaneous lipoma resection on his back (19 years previously). The patient underwent tumor resection with a right thoracotomy. A 58-year-old woman presented with an enlarging mass of the right lateral chest, involving the diaphragm and ribs, as seen by CT. She had a past history of subcutaneous lipoma resection of the right chest (18 years previously). The patient underwent an en bloc resection that included the tumor and a part of the right diaphragm and ribs. Histological examination of both patients' tumors revealed a well-differentiated liposarcoma, with no pathological relation to the previous lipoma resected in either case.

Review of Chest Wall Tumors: A Diagnostic, Therapeutic, and Reconstructive Challenge

“…21 Liposarcomas are one of the most common malignant soft tissue tumors in the body, but they are not common in the chest wall. 30 They are rarely found in children and are most common in men ages 40 to 60 years. It is not unusual for them to be large and frequently associated with trauma.…”

Dedifferentiated liposarcoma of the adult male breast

“…The dedifferentiated component in the axilla had spiculated margins. Computed tomography (CT) images can show solid masses with low densities representing fat ( 3 , 9 , 18 ). Several findings of liposarcoma on CT have been correlated histologically; hazy amorphous densities usually represent spindle formation, thick streaky structures represent entrapped muscle fibers, and thinner streaks represent fibrous tissue ( 19 ).…”

TłUszczakomięsak–Rzadki Pierwotny Nowotwór w Klatce Piersiowej

“…Obraz guza w TK zależy w dużym stopniu od jego struktury histologicznej, najczęściej ma on niejednorodny charakter, z ogniskami martwicy czy wylewów krwi w podścielisku nowotworu, często ze zwiększoną zawartością tkanki tłuszczowej i gęstością pośred-nią między tłuszczem a wodą od −80 do 0 HU, ale mogą też być to guzy o litym charakterze z niewielką zawartością tkanki tłuszczowej [10,15,16,23]. Zwykle nie stwierdza się powiększonych węzłów chłonnych w śródpiersiu [3,6,19].…”