2019
DOI: 10.1093/jscr/rjz352
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Giant plexiform schwannoma in the plantar aspect of the foot: a case report

Abstract: Plexiform schwannoma is a rare Schwann cell tumor that usually occurs in the head and neck. Here, we report a giant plexiform schwannoma (5.5 × 4.0 cm) in the right plantar aspect of the foot. This tumor presented from the dermis to the subcutaneous fat in the plantar aspect, forming a multiocular shape.

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Cited by 5 publications
(3 citation statements)
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“…The presence of multiple lesions represents a high risk of having NF2 and is associated with mutations of the NF2 gene on chromosome 22q12.2 (adjacent to the SMARCB1/INI1 suppressor gene) (12). Therefore, it is important to exclude the presence of associated dermal lesions and neurinoma in patients with PS, particularly in paediatric patients in whom inherited syndromes are more frequent, by performing thorough intracranial and spinal MRI examinations (11,13). Genetic studies are useful when there is a positive family history or in case of a certain association with NF-schwannomatosis.…”
Section: Discussionmentioning
confidence: 99%
“…The presence of multiple lesions represents a high risk of having NF2 and is associated with mutations of the NF2 gene on chromosome 22q12.2 (adjacent to the SMARCB1/INI1 suppressor gene) (12). Therefore, it is important to exclude the presence of associated dermal lesions and neurinoma in patients with PS, particularly in paediatric patients in whom inherited syndromes are more frequent, by performing thorough intracranial and spinal MRI examinations (11,13). Genetic studies are useful when there is a positive family history or in case of a certain association with NF-schwannomatosis.…”
Section: Discussionmentioning
confidence: 99%
“…Plexiform schwannomas (PSs) are rare benign peripheral nerve sheath tumour composed of schwann cells arranged in a complex, web-like pattern [193]. PSs are a morphologically distinct variant of schwannoma comprised exclusively of schwann cells.…”
Section: Plexiform Schwannomasmentioning
confidence: 99%
“…Plexiform schwannoma (PS), or neurilemmoma, is an uncommon benign tumor originating from a peripheral nerve sheath. It consists of Schwann cells organized in an intricate, web-like pattern [ 1 ]. The tumor primarily arises from Schwann cells' slow and progressive multiplication [ 2 ].…”
Section: Introductionmentioning
confidence: 99%