Giant Orf with Prolonged Recovery in a Patient with Psoriatic Arthritis Treated with Etanercept

Rørdam, Ole Martin; Grimstad, Øystein; Spigset, Olav; Ryggen, Kristin

doi:10.2340/00015555-1514

Cited by 12 publications

(20 citation statements)

References 7 publications

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“…3 However, immunocompromised patients are prone to large and refractory orf tumors. [2][3][4][5] Such rare, atypical forms of orf are frequently associated with the use of posttransplantation immunosuppressants, 3,6 such as glucocorticoids, cyclosporine, and tacrolimus. Clinically, the patients often present with pyogenic granuloma like lesions, 3,6 as noted in our case.…”

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confidence: 99%

“…Treatment of giant orf tumors in immunocompromised individuals typically relies on surgical excision, which is often followed by rapid postoperative recurrence. 2,3 To spare patients unnecessary surgeries, a number of topical medications such as idoxuridine, 3 cidofovir, 4 and imiquimod 5,6 have been documented. Among them, imiquimod cream alone or as an adjuvant with surgery appears to have lower recurrence rates, making it the most commonly used topical treatment in recent years.…”

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confidence: 99%

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Oral Acyclovir and Intralesional Interferon Injections for Treatment of Giant Pyogenic Granuloma–Like Lesions in an Immunocompromised Patient With Human Orf

et al. 2015

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roughly every 3.5 hours, to let the baby breastfeed and bond with her parents. Therefore, during each 24-hour period, she left the incubator 8 times, totaling 4 hours.The baby gained weight (indicating adequate oral intake) and maintained normal body temperature and blood chemistry values. On day 12, we increased her daily time out of the incubator to 6 hours by increasing the duration of incubator holidays to 60 minutes each and decreasing the number of incubator holidays to 6 (Table ). We decreased humidity by 10% per day from the incubator's 60% to the ambient 20% of the neonatal intensive care unit over days 12 to 16. This was well tolerated, and the baby was discharged to home on day 16. Genetic tests showed that she had autosomal recessive congenital ichthyosis, lamellar type.

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Oral Acyclovir and Intralesional Interferon Injections for Treatment of Giant Pyogenic Granuloma–Like Lesions in an Immunocompromised Patient With Human Orf

et al. 2015

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“…The therapeutic option that is first considered is often a surgical excision, although this Dear Editor, In psoriatic population, the Framingham risk score (FRS) has been used to assess the risk of major cardiovascular (CV) events for a 10-year follow-up period. [1][2][3][4][5][6] The established CV risk factors that are significant in models based on shorter follow-up duration are also related to CV disease (CVD) incidence in 30 years. 7,8 Nowadays, clustering of risk factors at younger ages and increasing life expectancy suggest the need for longer-term risk prediction tools.…”

Section: Giant Orf Tumour In An Immunocompromised Patientmentioning

confidence: 99%

Giant orf tumour in an immunocompromised patient

Polivka

Moguelet

Meritet

et al. 2017

Acad Dermatol Venereol

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“…Most of the infections in humans are localized and self-limiting. However, in immunosuppressive individuals large poorly healing lesions are seen including highly vascularized tumour, cauliflower-like mass of granuloma and painful lesions on skin (Rørdam et al, 2013). Further, human-to-human transmission has not been reported (CDC, 2012;Caravaglio et al, 2017).…”

Section: Clinical Signsmentioning

confidence: 99%