Giant orf in a normal individual

Abstract

A case of giant orf granuloma is described in a normal 12-year-old child. CASE REPORT

Conditions masquerading as infantile haemangioma: Part 2

“…[39][40][41] These were initially described in immunosuppressed patients, 38 but occur also in healthy individuals. [38][39][40] The fact that the lesion occurs outside the neonatal period makes the diagnosis of IH untenable, as does the usually speedy spontaneous resolution. The initial appearance on histopathology also mimics a vascular tumour with multiple dilated blood vessels and haemorrhage; however, there is also necrosis and marked inflammation, and detailed examination will reveal eosinophilic intranuclear inclusions.…”

Unusual Presentation of Orf in an Otherwise Healthy Individual

“…Our patient did not present a single giant orf nodule, but several homogeneous (10-15) nodules 1-1.5 cm in diameter, each in a single area of 10x8 cm. In addition, in our patient the orf virus infection was associated with concurrent skin trauma, which is a well-known facilitating factor for orf infection (4). As this case demonstrates, orf can easily be misdiagnosed.…”

“…Unusual presentations, such as giant orf, and widespread, papulovesicular or bullous lesions have been reported (1)(2)(3)(4)(5)(6)(7). Giant orf has been reported primarily in immunosuppressed individuals, but a few cases have been seen in otherwise healthy individuals.…”

“…Giant orf has been reported primarily in immunosuppressed individuals, but a few cases have been seen in otherwise healthy individuals. The giant orf lesions have typically been described as a single pedunculated tumour, several centimetres in diameter, attached to the skin by a round base of 2 cm diameter (1)(2)(3)(4)(5). in reported cases of widespread, papulovesicular or bullous lesions, the patients have been described as having typical orf lesions (1-3) on the fingers, followed some weeks later by widespread, papulovesicular or bullous lesions not resembling the initial orf lesions (6-7).…”

Viral diseases

“…Rapid diagnosis may be made by electron microscopy of the crust from an early lesion. 135 Lesions, which measure approximately 1-3 cm or more 132,133 in diameter, develop most commonly on the hands and forearms. 126,[130][131][132][133][134][135][136] It is caused by a poxvirus of the paravaccinia subgroup.…”