Introduction: Soft tissue sarcoma in adult is a rare disease and it needs an interdisciplinary team management. Liposarcoma has mesenchymal origin and arises in the fatty tissue. Multiple histologic subtypes of liposarcoma are recognized, including myxoid liposarcoma. In two-third of the cases, this tumor occurs in the muscle while often demonstrating a misleading benign appearance. Myxoid liposarcoma occurs predominantly in the deep soft tissues of the extremities and has the ability of metastasis to a wide range of soft tissue. Surgery is the main therapeutic modality in treatment of soft tissue sarcoma.
Case Report: Presenting an exceptional case of a 50-year-old woman with history of painless large swelling of size 28×21×13 cm in left gluteal region since one year with rapid progression over three months. It was diagnosed as low grade myxoid liposarcoma of the left buttock. This is the largest reported case of myxoid liposarcoma of extremities in Asia found in literature. The patient was treated with complete excision of tumor with gluteus maximum muscle. Gluteus minimus flap was elevated to cover the exposed sciatic nerve and buttock recontouring was done as single procedure for aesthetically favorable results followed by post-operative radiotherapy and necessary follow-ups.
Conclusion: Buttock contouring done post-resection as single procedure is more acceptable by the patient and has got superior aesthetic results.