2015
DOI: 10.1016/j.ijid.2015.07.021
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Giant Molluscum Contagiosum in an HIV positive patient

Abstract: Molluscum Contagiosum (MC) is a skin infection caused by a double-stranded DNA virus of the family Poxviridae that replicates in the human epidermis, affecting mainly children and young sexually active adults and causing flesh colored papular lesions with central umbilication with an average size of 3-5mm, although atypical lesions that reach great size (Giant Molluscum Contagiosum), 10-15mm, can be seen in almost any immunodeficiency condition. We report the case of a 35 year old male patient with C3 HIV dise… Show more

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Cited by 17 publications
(11 citation statements)
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“…Molluscum contagiosum (MC) is a common infectious disease of the skin characterized by pearly dome-shaped papules with a central dell or depression located on the face, arms, legs and anogenital region, caused by the molluscum contagiosum virus [1]. The virus replicates in the epidermis and enters the skin from a small skin defect leading to impaired skin barrier function or from contaminated items, such as towels or clothes.…”
Section: Discussionmentioning
confidence: 99%
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“…Molluscum contagiosum (MC) is a common infectious disease of the skin characterized by pearly dome-shaped papules with a central dell or depression located on the face, arms, legs and anogenital region, caused by the molluscum contagiosum virus [1]. The virus replicates in the epidermis and enters the skin from a small skin defect leading to impaired skin barrier function or from contaminated items, such as towels or clothes.…”
Section: Discussionmentioning
confidence: 99%
“…The virus replicates in the epidermis and enters the skin from a small skin defect leading to impaired skin barrier function or from contaminated items, such as towels or clothes. Specific lesions of MC are usually smaller than 5 mm and less than 20 in number [14]. Although it is known to be a disease of childhood, rarely it can be seen in adults.…”
Section: Discussionmentioning
confidence: 99%
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“…1 A doença é geralmente mais grave nos doentes com infeção pelo VIH e redução marcada dos linfócitos T CD4 + . [1][2][3] Clinicamente podem existir múltiplas lesões típicas (pápulas umbilicadas com menos de 1 cm) e/ou atípicas (mais de 2 cm, confluentes), colocando dificuldades no diagnóstico diferencial com condilomata lata (sífilis secundária) e condilomas acuminados. 4 Embora possa ocorrer resolução espontânea com terapêutica antirretroviral, as lesões podem mostrar-se resistentes e recidivantes.…”
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