Giant mediastinal chordoma

An unusual presentation of chordoma as a pyloric ring submucosal tumor: The first case report of a primary gastrointestinal lesion in humans

“…Extra-axial–skeletal primary cases of the ulna, tibia, femur, and pubic bone have been reported [7] , [8] , [9] . Although extra-skeletal primary cases are exceptionally rare, they have been reported to occur in a wide variety of locations, including the toes, fingers, buttocks, chest wall, shoulders, thighs, hands, wrist joints, nasopharynx, and posterior mediastinum [7] , [10] , [11] , [12] , [13] , [14] . No other reports on extra-skeletal chordomas originating in the gastrointestinal wall have been previously published in literature.…”

Thoracic Chordoma Misdiagnosed as Primary Adenocarcinoma of the Mediastinum

“…The mass in this case did not show any evidence of differentiation, thus the diagnosis was chordoma not otherwise specified. Its strong tendency to recur at surgical sites and the fair chance of refractory behavior to therapeutic modalities (radiation, systemic agents) may prove lethal [4]. Thoracic chordoma pre- Vertebral body destruction may be evident radiographically.…”