Giant malignant fibrous histiocytoma of the testis/spermatic cord: Psychologic and possible etilogic complications of unethical Nazi medical experimentation

Staiman, Victoria R.; O’Toole, Kathleen; Rubin, Mark A.; Lowe, Franklin C.

doi:10.1016/s0090-4295(96)00319-6

Cited by 22 publications

(22 citation statements)

References 12 publications

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“…MFH of the testicle is a very rare tumor and only 4 cases have been reported, 2 of which are in English. [5,6] The ages of the reported patients ranged from 14 to 78 years. The pathogenesis of MFH is unknown.…”

Section: Discussionmentioning

confidence: 99%

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Giant malignant fibrous histiocytoma of the testis

Ülker¹,

Atalay²,

Çakır³

et al. 2018

Turkish Journal of Urology

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We present a case of malignant fibrous histiocytoma of the testis in a 59 year-old male who admitted to our hospital with left testicular painless mass presenting for two months. A scrotal ultrasound examination and magnetic resonance imaging revealed a 9 cm left testicular solid mass. Serum tumor markers were unremarkable. The patient underwent left radical orchiectomy. Histopathologic diagnosis was giant cell variant of malignant fibrous histiocytoma which composed of varying amounts of a mixture of spindled, rounded and osteoclastic type giant cells. Hemorrhagic and necrotic areas were seen between tumor nodules. In immunohystochemical staining, vimentin, CD68 were positive and SMA was focally positive. The patient then received adjuvant chemoterapy and currently, he has no sign of recurrence.

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Section: Discussionmentioning

confidence: 99%

“…A limited number of cases of MFH originating from spermatic cord have been reported in the literature [3,4] , however, testicular localisation of MFH is very rare and there are only a few reported cases. [5,6] In this case we present a giant cell variant of testicular MFH and discuss its treatment and prognosis.…”

Section: Introductionmentioning

confidence: 97%

Giant malignant fibrous histiocytoma of the testis

Ülker¹,

Atalay²,

Çakır³

et al. 2018

Turkish Journal of Urology

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“…The tumor cells have features suggestive of fibroblastic, myofibroblastic, and/or histiocytic origin and may have developed from the fibrous tissue of the spermatic cord and paratesticular areas, such as tunica albuginea (33). One of the previously reported cases arose in a man who received intratesticular injection of an unknown substance in a Nazi concentration camp 40 years before developing paratesticular MFH (35).…”

Section: Discussionmentioning

confidence: 99%

Malignant Fibrous Histiocytoma of the Spermatic Cord: Report of Two Cases and Review of the Literature

2002

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“…MFH is also a rare subtype of STS of the spermatic cord (8). Long-term survival is possible and local lymph node involvement is rare.…”

Section: Discussionmentioning

confidence: 99%

“…In one case a malignant fibrous histiocytoma of the testis was found in a Holocaust survivor who was injected with an unknown substance in the left testicle while in Auschwitz concentration camp (8).…”

Section: Discussionmentioning

confidence: 99%