Giant magnetoimpedance biosensor for ferrogel detection: Model system to evaluate properties of natural tissue

Kurlyandskaya, G.V.; Férnández, Eduardo F.; Сафронов, А. П.; Svalov, A. V.; Бекетов, И. В.; Burgoa, Aizeti; Garcı́a-Arribas, A.; Blyakhman, F. A.

doi:10.1063/1.4921224

Cited by 73 publications

(62 citation statements)

References 20 publications

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“…Those were exhaustively reviewed recently [72]. Among the different materials used, besides wires and ribbons, thin film structures have been demonstrated to be able to detect microparticles in a flowing liquid [73] and nanoparticles embedded in gels (ferrogel) [74]. In these works, the presence of magnetic particles modifies the magnetic permeability on the medium surrounding the MI element, producing the measured changes in the impedance.…”

Section: Brief Survey Of Applicationsmentioning

confidence: 99%

Thin-Film Magneto-Impedance Sensors

Garcı́a-Arribas¹,

Férnández²,

Cos³

2017

Magnetic Sensors - Development Trends and Applications

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We review the state-of-the-art of thin films displaying the magneto-impedance (MI) effect, with focus on the aspects that are relevant to the successful design and operation of thin film-based magnetic sensors. After a brief introduction of the MI effect, the materials and geometries that maximize the performance, together with the measurement procedure for their characterization, are exposed. A nonexhaustive survey of applications is included, mostly with the aim of displaying the capabilities of thin film structures in the field of magnetic sensing, and the variety of topics covered by them. A special emphasis is made on some concepts that are not commonly treated in the literature, such as the influence of the measuring circuit on the magneto-impedance ratio, the geometry optimization by means of numerical simulation by finite element methods, or noise measurements on thin films. Additionally, a brief description of the patterning procedure by photolithography is included, since the major advantage of thin film sensors over other types of magneto-impedance materials as ribbons or wires is the possibility of patterning the sensible element in micrometric shapes, and most of all, their easy integration with the interface microelectronic circuitry.

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Section: Brief Survey Of Applicationsmentioning

confidence: 99%

Thin-Film Magneto-Impedance Sensors

Garcı́a-Arribas¹,

Férnández²,

Cos³

2017

Magnetic Sensors - Development Trends and Applications

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“…GMI effect in soft magnetic materials seems to be quit promising for applications in the technological area of small magnetic field sensors and magnetic biosensors [2,3]. The idea of a biosensor based on amorphous ribbon is attractive since this would allow construction of a cheap detector with the sensitive element designed as a disposable strip.…”

Section: Introductionmentioning

confidence: 99%

“…Previous studies showed that the GMI responses in appropriate conditions can be clearly dependent on the presence of the magnetic ferrofluid and the parameters of the driving current [3,6]. The shape or particular geometry of the sensitive element strongly influences the GMI behavior.…”

Section: Introductionmentioning

confidence: 99%

“…GMI has been proposed as a powerful technique for biosensing based on the magnetic label detection or label-free sensing process. In the first case the change of the impedance of sensitive element under the application of an external magnetic field is analyzed in the presence of magnetic nanoparticles (MNPs) in a test solution and the origin of the sensitivity is clearly connected with the stray fields crated by the MNPs [3,4]. In the second case if rapidly quenched ribbon sensitive element is employed the advantage of natural nonuniform magnetic anisotropy was taken [5].…”

Section: Introductionmentioning

confidence: 99%

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Magnetoimpedance Effect in CoFeMoSiB As-Quenched and Surface Modified Amorphous Ribbons in the Presence of Igon Oxide Nanoparticles of Water-Based Ferrofluid

et al. 2017

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Giant magnetoimpedance (GMI) has been proposed as a powerful technique for biosensing. In GMI biosensors based on the magnetic label detection the change of the impedance of sensitive element under the application of an external magnetic field was analyzed in the presence of magnetic nanoparticles in a test solution. Amorphous ribbon-based GMI biodetectors have an advantage of low operation frequency and low cost. In this work, magnetic and GMI properties of amorphous Co 68.6 Fe 3.9 Mo 3.0 Si 12.0 B 12.5 ribbons were studied in as-quenched and surface modified states both without and in the presence of maghemite ferrofluid. After the surface modification the coercivity was slightly increased and saturation magnetization decreased in good agreement with increase of the surface roughness, a decrease of magnetic elements concentrations in the surface layer, and formation of a surface protective oxide layer. The GMI difference for as-quenched ribbons in absence and in the presence of ferrofluid was measurable for the frequency range of 2 to 10 MHz and the current intensities of 1 to 20 mA. Although the proposed surface modification by the ultrasound treatment did not improve the sensitivity limit for ferrofluid detection, it did not decrease it either.

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“…PAAm is a water soluble biocompatible polymer and it can form chemically cross-linked networks of homogeneous hydrogels with the network density varying in a broad range. The application of PAAm ferrogels as a potential material for biosensors had been demonstrated [15]. The conventional approach in the studies on polyacrylamide ferrogels is focused on their magnetic properties and their response to the applied magnetic field.…”

Section: Introductionmentioning

confidence: 99%

Interaction of iron oxide nanoparticles synthesized by laser target evaporation with polyacrylamide in composites and ferrogels

2017

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Iron oxide magnetic nanoparticles (MNPs) with average diameter 11.7 nm synthesized by laser target evaporation were used for the synthesis of composites and ferrogels based on polyacrylamide network. The chemical composition of MNPs corresponded to maghemite. It was shown that intact MNPs strongly interacted with polyacrylamide polymeric network, while the adsorption of electrostatic stabilizer on the surface of MNPs efficiently prevents such interaction. Synthesis of ferrogels was performed by the radical polymerization of acrylamide in electrostatically stabilized suspensions of MNPs in water. It was shown that the molecular structure, water uptake, and compression modulus can be controlled by the concentration of monomer taken in the synthesis.

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Giant magnetoimpedance biosensor for ferrogel detection: Model system to evaluate properties of natural tissue

Cited by 73 publications

References 20 publications

Thin-Film Magneto-Impedance Sensors

Thin-Film Magneto-Impedance Sensors

Magnetoimpedance Effect in CoFeMoSiB As-Quenched and Surface Modified Amorphous Ribbons in the Presence of Igon Oxide Nanoparticles of Water-Based Ferrofluid

Interaction of iron oxide nanoparticles synthesized by laser target evaporation with polyacrylamide in composites and ferrogels

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