Giant Lipomas: A Series of 12 Consecutive Cases and a Giant Liposarcoma of the Thigh

Abstract

When dealing with giant lipomas, liposarcomas should always be included in the differential diagnosis.

A case report of an intermuscular lipoma: presentation, pathophysiology, differential diagnosis

“…After complete resection, there is a 1% recurrence rate compared with a 19% recurrence rate of intramuscular lipomas. 13 Deep lipomas that are either intermuscular or intramuscular have been described as infiltrating lipomas by Terzioglu et al 3 Lipomas are more likely to be encapsulated in the shoulder than in the thigh. 9 Tumors within the popliteal or inguinal region may compromise neurovascular bundles through encasement.…”

“…In this case, the MRI measurements of the 3,16 or atypical adipocytes 17 would raise the concern for liposarcoma. Histologically, lipomas resemble normal fat, whereas well-differentiated liposarcomas, although similarly resembling 9 fat histologically, also have dense bands of collagen traversing the mass with associated gelatinous areas.…”

“…1 Lipomas are composed of mature lipocytes. 2,3 The most common malignant soft tissue www.journalchiromed.com mass is malignant fibrous histiocytoma followed by liposarcoma, which resembles lipomas on computed tomography (CT) and magnetic resonance imaging (MRI) 4 and is most common in the thigh. 5 Solitary lipoma occurs with equal frequency in males and females, with multiple lipomas more common in males.…”

“…The muscular lipomas can be infiltrating. 3 The deep lipoma often presents without clinical symptoms and therefore grows to a large size before detection. 3 Lipomas are typically asymptomatic unless they compress neurovascular structures.…”

“…3 The deep lipoma often presents without clinical symptoms and therefore grows to a large size before detection. 3 Lipomas are typically asymptomatic unless they compress neurovascular structures. 7 Given the prevalence of lipoma and the likelihood of soft tissue masses being discovered during clinical examinations, the intent of this article is to describe a recent case presentation and discuss the pathophysiology of lipomas, differential diagnosis, imaging characteristics, and the range of treatment options.…”