Giant lipoma in superior vena cava: A case report and literature review

Mobile primary renal vein lipoma with an accelerated growth pattern

“…A few studies have documented the slow-growing nature of this tumor. 4 , 9 In contrast, our case is unique because the primary renal vein lipoma had exhibited aggressive growth behaving like that of malignant tumors, as evident from the serial imaging studies, but without invading the neighboring tissue and metastasizing. This raised concerns for possible malignancy, especially given our patient’s age.…”

“…Most cases are symptom-free, discovered incidentally on imaging studies, and mainly located within the IVC 1 . Intravenous lipomas are also less frequently reported in several other locations such as the superior vena J o u r n a l P r e -p r o o f cava(SVC) 4 , brachiocephalic 5 , subclavian 6 , common femoral 7 , and external iliac veins 8 . There are only two cases arising from the wall of renal veins, both of which were managed conservatively 2,3 .…”

“…The growth rate of primary intravascular lipomas is not well described in the literature. A few studies document the slow-growing nature of this tumor 4,9 . By contrast, our case is unique because the primary renal vein lipoma exhibited aggressive growth behaving like that of malignant tumors, as evident on serial imaging studies, without invading neighboring tissue and metastasizing.…”

“…Conservative management is the standard care for centrally located primary intravascular lipomas, and surgical resection is only indicated in symptomatic 10 . Most large and symptomatic tumors were surgically removed with limited complications 4,11,12 . The commonly reported symptoms included swelling and dyspnea [13][14][15] .…”

“… 10 Most large and symptomatic tumors were surgically removed with limited complications. 4 , 11 , 12 The commonly reported symptoms included swelling and dyspnea. 13 , 14 , 15 A few asymptomatic patients had undergone surgical excision because of concerns for embolization or malignancy.…”