Giant intercostal nerve schwannoma in a patient with neurofibromatosis type 2

Ampollini, Luca; Ventura, Luigi; Gnetti, Letizia; Carbognani, Paolo; Silini, Enrico Maria; Rusca, Michele

doi:10.1177/0300891618778950

Cited by 3 publications

(1 citation statement)

References 26 publications

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“…Pathologically, schwannoma was composed of Antoni type A and Antoni type B. the tumor was encapsulated without axons, and there might be blood vessels in the tumor, the speci c immunohistochemical features of schwannoma including S-100 protein, vimentin and enolase were positive, while neuro lament protein was negative (10,14,15). In particular, S-100 protein can be seen in almost all schwannomas and is a marker of benign schwannomas (15,16).…”

Section: Discussionmentioning

confidence: 99%

Schwannoma of Left Chest Wall: a Case Report and Literature Review

Tang

Qin

et al. 2021

Preprint

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Background: Schwannoma of chest wall is rare intercostal nerve tumor originated from Schwann cells. Here, we present a rare case about schwannoma was misdiagnosed as solitary fibroma by preoperative biopsy. We intend to improve clinicians' understanding of the disease by discussing the clinical manifestations, diagnostic points and differential diagnosis of patients with thoracic wall schwannoma.Case presentation: A 38-year-old male presented with "left chest pain for more than 1 month". Enhanced Computer Tomography(CT) can of the lung revealed space occupying lesions in the left lower posterior chest wall. Preoperative biopsy was solitary fibroma. After the improvement of preoperative preparation, the patients were given surgical treatment, postoperative pathology showed: schwannoma of chest wall. Chest pain improved after operation. The patients were followed up for 8 months.Discussion and Conclusions: Schwannoma, especially in the chest wall, is rare, with atypical clinical symptoms, single imaging manifestations, high variable rate of puncture pathology, and easy to be misdiagnosed. Complete surgical resection of tumor is the main treatment, and no new adjuvant / adjuvant therapy has been reported yet.

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