Giant Hypertrophic Gastritis and Acute Hepatitis Associated with Cytomegalovirus Infection.

Abstract

A 38-year-old man developed prominent hypoproteinemia after acute elevation of serum transaminase levels. Giant hypertrophy of the gastric mucosa, a short serum albumin half-life, and the absence of massive hepatocyte necrosis established the diagnosis of protein-losing gastropathy. The hypoproteinemia, gastric fold hypertrophy and hepatitis remitted sponta neously within 4 months. A high antibody titer against cytomegalovirus suggested an association between the viral infection and the patient's disease. (Internal Medicine 31: 816-819, 1992)

Cytomegalovirus-associated Acute Gastric Mucosal Lesion in an Immunocompetent Host

“…CMV can cause ulcerations anywhere in the GI tract ranging from the esophagus to the rectum (1-3, 9, 11-13 (14,15).…”

Multiple Large Gastric Ulcers as a Manifestation of Cytomegalovirus Infection in a Healthy Child

“…may include bleeding and perforation (12). It should be kept in mind that CMV gastritis is not a disease exclusive to the immunocompromised host, as illustrated in this and other reports (4,5,13). Therefore, the differential diagnosis of hypertrophic and erosive gastritis should include CMV infection in both immunocompromised and immunocompetent patients.…”