Giant Haemangioma in the Newborn

Abstract

EDITORIAL SYNOPSIS A review of case reports from the literature and patients personally studied by the authors delineates the natural history of the condition, indicating that if early complications are successfully managed spontaneous involution of the tumour may be expected, radical surgery minimized and later cosmetic surgery achieve a satisfactory result.

Giant Hemangioma Presenting as a Scalp Mass Leading to a Craniofacial Deformity

“…In some cases, these lesions do not regress and they continue to grow and reach large dimensions [3][4][5][6][7][8][9][10][11]. Cases of giant hemangiomas forming masses that deform the scalp as the case reported here have rarely been reported in the literature [4][5][6][7][8][9][10][11], especially in adults [4].…”

“…In about 70% of cases, after this stage, there is a growth arrest followed by a regression phase [2,4] that can last up to 10-12 years of age [1,4]; antiangiogenic factors (tissue inhibitor of metalloproteinase, mast cells, and scavenger macrophage) are involved with this regression [1]. In some cases, these lesions do not regress and they continue to grow and reach large dimensions [3][4][5][6][7][8][9][10][11]. Cases of giant hemangiomas forming masses that deform the scalp as the case reported here have rarely been reported in the literature [4][5][6][7][8][9][10][11], especially in adults [4].…”

“…There is no clear definition about what size a lesion should achieve to be regarded as a giant hemangioma [6,7]. Colebatch et al [11] described the giant hemangioma as a tumor with a diameter of at least 5-6 cm.…”

“…Most lesions tend to regress by 10 years of age [1,2] and, in some cases, tumors can achieve large dimensions [3][4][5][6][7][8][9][10][11]. There is no clear definition about what size a lesion should achieve to be regarded as a giant hemangioma [6,7].…”