Giant fibrokeratoma, a rare soft tissue tumor presenting like an accessory digit, a case report and review of literature

Abstract

HighlightsGiant digital fibrokeratoma, nail like changes, benign growth, surgical excision.

Acquired digital fibrokeratoma: A case report and review of the literature

“…However, very few cases have been described to adequately assess the significance of any sex predilection of this tumor type. Reported acquired digital fibrokeratoma cases have occurred in patients from 12 to 70 years of age, with most cases occurring in middle-aged adults [11] . Most patients with acquired digital fibrokeratoma present with an asymptomatic protuberance that gradually increases in size over time [12] .…”

“…Typically, ADFKs are small and less than 1 cm in diameter. Ali et al and Choi et al reported 3.0 × 1.6 × 1.2-cm and 2.5 × 1.6 × 1.4-cm ADFKs on the toe, respectively, and designated them as giant ADFKs [11,13] . Frydman et al reported a 4.0 × 1.5-cm ADFK on a left foot [12] .…”

“…ADFKs are predominantly, although not exclusively, located on the fingers and toes near the phalangeal joints [16] . Occasionally, they occur on the elbow, wrist, calf, and prepatellar [11] . ADFKs are almost always solitary, and only two case reports have described ADFK being accompanied by another tumor [11] : one report described a renal transplant patient on cyclosporine who developed an ADFK on a toe simultaneously with a gingival overgrowth, and the authors suggested that there may have been a causal association between these two growths [12] ; another report described an ADFK accompanied by a pyogenic granuloma [17] .…”

“…Occasionally, they occur on the elbow, wrist, calf, and prepatellar [11] . ADFKs are almost always solitary, and only two case reports have described ADFK being accompanied by another tumor [11] : one report described a renal transplant patient on cyclosporine who developed an ADFK on a toe simultaneously with a gingival overgrowth, and the authors suggested that there may have been a causal association between these two growths [12] ; another report described an ADFK accompanied by a pyogenic granuloma [17] . Histopathological examination shows epidermal hyperkeratosis and acanthosis of the epidermis and the core of the lesion is formed of interwoven bundles of collagen predominantly oriented along the long axis of the lesion [18] .…”

Acquired digital fibrokeratoma: review of its clinical and dermoscopic features and differential diagnosis

“…ADFK is typically asymptomatic and occurs as a solitary, flesh‐colored papule or nodule less than 1 cm in diameter (Fig. ), but less commonly it may present as a symptomatic nodule much larger than 1 cm and can cause significant pain, also known as giant acquired digital fibrokeratoma . It most commonly occurs on the fingers but can also be seen on the palm, toes, and sole .…”