Giant fibroepithelial polyp of the thigh and retroperitoneal fibromatosis in a young woman: a rare case

Gupta, Ruchika; Smita, Shuchi; Sinha, Ruchi; Sinha, Neetu; Sinha, Lakshmi

doi:10.1007/s00256-018-2904-x

Cited by 4 publications

(2 citation statements)

References 14 publications

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“…Dimensions usually range between 1-2 mm and 1-2 cm, but giant fibroepithelial polyps have been reported. A 40 cm × 25 cm tumor has been reported by Gupta et al [11] Differential diagnosis include leiomyoma, sarcoma, and pedunculated neurofibromas. [12] Pilar cysts or trichilemmal cysts (TCs) are thought to be derived from the outer sheet of hair follicles.…”

Section: Discussionmentioning

confidence: 93%

Giant benign skin tumors: A retrospective analysis and compilation of noteworthy characteristics

Tatar¹,

Sezgin²,

Özmen³

2020

Turk J Plast Surg

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IntroductIonBenign skin tumors are soft-tissue lesions that frequently present with poor cosmesis along with pain, functional limitations, deformity, and hypoesthesia depending on the location. [1] Numerous histopathological subtypes, including lipomas, epidermoid cysts, fibroepithelial polyps, neurofibromas, pilar cysts, and xanthomas have been described, ranging from 1 to 2 mm to giant dimensions. [1][2][3] The term "giant benign tumor" is usually described and categorized individually for different tumor types. Although benign skin tumors progress slowly and are usually asymptomatic, rapid progression and giant forms should be evaluated and differentiated from malignant transformation.The purpose of this study was to evaluate patients operated for giant benign skin tumors in our department and to compile noteworthy characteristics regarding each tumor subtype regarding surgical indications, size, location, and histopathological results and follow-up. MaterIals and MethodsFollowing the approval of the Clinical Studies Board of Ethics, this study included a total of 16 consecutive patients who underwent surgery for giant benign skin tumors between 2015 and 2018 based on the literature definition of "giant benign skin tumors." Written informed consent was obtained from all patients, and the study protocol was compliant with the guidelines of the Declaration of Helsinki. Demographic parameters, indications, symptoms, pathological results, and postoperative complications were evaluated retrospectively.Background/Aim: Benign skin tumors are soft-tissue lesions that present with poor cosmesis along with pain, functional limitations, deformity, and hypoesthesia. Rapid progression and giant forms should be evaluated and differentiated from malignant transformation. The aim of this study is to evaluate the patients operated for giant benign skin tumors and to assess clinical experience about indications, size, location, and histopathological results and follow-up period. Materials and Methods: The present study included 16 consecutive patients who underwent surgery for giant benign skin tumors between 2015 and 2018 based on the literature definition of "giant benign skin tumors." Demographic parameters, indications, symptoms, pathological results, and postoperative complications were evaluated retrospectively. Results: Sixteen patients (11 males and 5 females) were operated for giant benign skin tumors. The mean age of the patients was 53.38 (range: 37-72) years. Tumor locations were on the scalp for four patients, the upper extremity for three patients, lower extremity for three patients, trunk for five patients, and generalized for one patient. Pain was the most common symptom, and hypoesthesia, functional limitations, ulceration, and infection were also observed. Total excision was performed for all patients. No major complications and recurrence were observed. Conclusion: Clinical follow-up is an option for patients presenting to clinic with lesions that are small in size and asymptomatic. However, a detailed histor...

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Section: Discussionmentioning

confidence: 93%

Giant benign skin tumors: A retrospective analysis and compilation of noteworthy characteristics

Tatar¹,

Sezgin²,

Özmen³

2020

Turk J Plast Surg

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“…In the literature, FEPs larger than 15 cm have been reported in the following locations: vulva, [2] axilla, [7] and thigh. [9,10] There are various hypotheses about why FEPs grow that much. It has been proposed that the epithelium of the FEPs located in the genital tract are hormone-sensitive, and extended hormone intake, pregnancy or hormonal changes can trigger their growth.…”

Section: Discussionmentioning

confidence: 99%

Giant Fibroepithelial Polyps: Why Do They Grow Excessively?

Can

Özlük

2018

Sisli Etfal

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F ibroepithelial polyps or acrochordons are benign tumors of mesenchymal and ectodermal origin. They frequently occur in places where skin folds are present. Generally, their size does not exceed 5 millimeters. However, a case with a 42 centimeters long FEP has been reported in the literature. [1] There are different opinions about how FEPs reach these sizes and what triggers the growth. It is stated that the sensitivity of epithelium to hormones and hormonal changes may be the cause of the growth of FEPs, which are located in the genital tract and reached huge sizes. [2] It is also remarkable that FEPs located in this area are seen more frequently in women and in reproductive age. [3] It is not known exactly what triggered the growth of the FEPs that are located in other locations and reached huge sizes. However, a positive correlation between obesity, insulin resistance and FEP growth has been proposed. [4][5][6] Our case was unique concerning the FEP location. We did not find a similar case in terms of location and size in the literature. Our patient also had a ventriculoperitoneal shunt for six years due to idiopathic hydrocephalus. The shunt was 2 centimeters away from FEP. It may be thought that the foreign body reaction in this area may be an effect on FEP growth. In this report, we aimed to present our approach to a giant FEP and to examine the factors that cause FEP growth.

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CT and MR imaging findings of solitary nevus lipomatosus cutaneous superficialis: radiological–pathological correlation

et al. 2019

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Giant fibroepithelial polyp of the thigh and retroperitoneal fibromatosis in a young woman: a rare case

Cited by 4 publications

References 14 publications

Giant benign skin tumors: A retrospective analysis and compilation of noteworthy characteristics

Giant benign skin tumors: A retrospective analysis and compilation of noteworthy characteristics

Giant Fibroepithelial Polyps: Why Do They Grow Excessively?

CT and MR imaging findings of solitary nevus lipomatosus cutaneous superficialis: radiological–pathological correlation

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