Giant Esophageal Liposarcoma

Ogami, Takuya; Bozanich, Nadia; Richter, Joel E.; Velanovich, Vic

doi:10.1007/s11605-017-3545-4

Cited by 2 publications

(5 citation statements)

References 3 publications

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“…and 11 additional case reports from the review of PubMed as described above, with duplicates excluded[2][3][4]6,[9][10][11][12][13][14][15]. Our case represents the 77th reported case of esophageal liposarcoma.…”

mentioning

confidence: 90%

“…They are derived from primitive mesenchymal cells and usually arise from the esophageal submucosa [3]. Since the publication of the first case report in 1983, 76 cases of esophageal liposarcoma have been reported in the English-language medical literature [2][3][4][5][6][7][8][9][10][11][12][13][14][15][16]. The clinical presentation of these tumors is usually with symptoms of dysphagia, dyspnea, or, in some cases, regurgitation of the mass [2].…”

Section: Introductionmentioning

confidence: 99%

“…The clinical presentation of these tumors is usually with symptoms of dysphagia, dyspnea, or, in some cases, regurgitation of the mass [2]. Evaluation often reveals a pedunculated intraluminal mass, which may be visible on contrast esophagography [3,4]. Esophageal liposarcomas are associated with a better prognosis than their conventional counterparts at other sites and usually do not metastasize from their primary location [5].…”

Section: Introductionmentioning

confidence: 99%

“…The WHO histological classification includes well-differentiated, dedifferentiated, myxoid, and pleomorphic subtypes [1]. Imaging studies, such as magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET), may be useful in the diagnostic process and surgical planning [4,6]. Biopsy and immunohistochemistry for MDM2 gene locus amplification remain critical for diagnosis [7].…”

Section: Introductionmentioning

confidence: 99%

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Esophageal Liposarcoma: A Case Report and Review of the Literature

Boghani,

Compton,

Postma

et al. 2023

Cureus

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Liposarcomas are extremely rare occurrences in the esophagus. Here, we present an unusual case of esophageal liposarcoma that contributed to a long history of dysphagia before a definitive diagnosis was reached. The case is that of a 61-year-old woman who complained of dysphagia and foreign body sensation in her throat and was found to have a large filling defect within the cervical esophagus on barium esophagogram. She underwent endoscopic resection of the mass and was diagnosed with a five-centimeter long, well-differentiated esophageal liposarcoma, confirmed with fluorescence in situ hybridization for MDM2 gene locus amplification. Subsequent laser ablation of the tumor bed was conducted with no recurrences noted to date. Proper histologic identification, alongside adjunctive cytogenetic and molecular diagnostics, followed by definitive surgical resection and extended follow-up, are emphasized as critical in optimizing outcomes for this disease. A review of the existing English-language medical literature relating to esophageal liposarcoma was performed and summarized.

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confidence: 90%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Esophageal Liposarcoma: A Case Report and Review of the Literature

Boghani,

Compton,

Postma

et al. 2023

Cureus

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show abstract

“…Eighty percent of esophageal liposarcoma is situated in the cervical segment of the esophagus. [ 3 4 ] The tumor usually grows slowly and the common symptoms include dysphagia and regurgitation, after surgery, the favorable prognosis is usually achieved. The imaging diagnosis of this disease mainly depends on the examination of computed tomography (CT) and endoscopic ultrasound (EUS), the preoperative pathology is usually acquired by the operation of EUS-guided or esophagoscopic biopsy.…”

Section: Introductionmentioning

confidence: 99%