Giant epithelial-myoepithelial carcinoma of the parotid gland

Maurer, Martin; Gartenschläger, S.; Dietrich, Christoph F.

doi:10.1016/j.clinimag.2008.11.013

Cited by 10 publications

(13 citation statements)

References 10 publications

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“…The 5-year and 10-year survival of patients following complete surgical excision were 93.5% and 81.8%, respectively, in a study by Seethala et al and 87% and 67.5%, respectively, in a study by Maurer et al (13,15). tion, and drafting of the manuscript; All the authors critically reviewed and approved the final manuscript.…”

Section: Final Diagnosismentioning

confidence: 98%

A Rare Case of Clear Cell Carcinoma of the Parotid Gland in Iran

Saberi

Modabbernia

2016

Iran Red Crescent Med J

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Introduction: Salivary gland tumors are rare head and neck lesions. The majority are benign, with only 20% of cases malignant. An epithelial-myoepithelial carcinoma is a rare low-grade malignant salivary and lacrimal gland tumor, which accounts for less than 1% of salivary gland tumors. It mostly involves the parotid gland and affects adults in their sixth and seventh decades. It is usually painless, unless the minor salivary glands are affected. Case Presentation: We describe a rare case of a 35-year-old woman who presented with a 1-year-old unilateral painful parotid swelling in December 2014. Conclusions: A complete immunohistochemical study should be considered in cases of malignant salivary gland tumors. To reduce the recurrence rate of these tumors, the optimum therapies are radiotherapy and chemotherapy.

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Section: Final Diagnosismentioning

confidence: 98%

A Rare Case of Clear Cell Carcinoma of the Parotid Gland in Iran

Saberi

Modabbernia

2016

Iran Red Crescent Med J

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“…10 Atypical features such as rapid and/or painful growth may portend a highergrade lesion with a more aggressive clinical course. 10 Atypical features such as rapid and/or painful growth may portend a highergrade lesion with a more aggressive clinical course.…”

Section: Epithelial-myoepithelial Carcinomamentioning

confidence: 99%

Epithelial-Myoepithelial Carcinoma of Salivary Glands

Turk¹

2015

Pathology Case Reviews

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Primary clear cell tumors of the salivary glands include epithelial-myoepithelial carcinoma, clear cell carcinoma, and clear cell myoepithelial carcinoma. Epithelial-myoepithelial carcinoma comprises intercalated duct-like structures with an inner component of epithelial cells, surrounded by an outer component of clear myoepithelial cells. Clear cell carcinoma consists exclusively of luminal-type epithelial cells, whereas myoepithelial carcinoma shows only cells that demonstrate myoepithelial differentiation.Clear cell predominance within myoepithelial carcinoma is rare but well described. Despite several commonalities between these entities, various features distinguish them from one another. Epithelialmyoepithelial carcinoma and clear cell carcinoma are more common among female patients, whereas clear cell myoepithelial carcinoma occurs equally frequently in men and women. Epithelial-myoepithelial carcinoma and clear cell myoepithelial carcinoma characteristically affect the parotid gland and show multinodular expansive growth, whereas clear cell carcinoma usually arises in minor salivary glands and invades as smaller cellular nests. Molecular studies have identified chromosomal rearrangements involving EWSR1 (most frequently creating EWSR1-ATF1 fusion) in approximately 80% of clear cell carcinoma cases. The distinctive characteristics of these lesions are important to understand and consider, given the substantial morphologic and clinical overlap between them. The similarities and differences among these 3 entities constitute the focus of this review.An 84 year-old woman sought medical attention for a painless lump in her left cheek, which she had noticed incidentally 8 months previously. Upon physical examination, her primary care physician noted a mass near the angle of the left mandible. Ultrasound and magnetic resonance imaging confirmed the presence of a lesion in the superficial anterior aspect of the left parotid gland; radiologic findings were otherwise nonspecific. Fine-needle aspiration showed cellular clusters of basaloid cells, and the cytology specimen was interpreted as "salivary gland neoplasm." The patient subsequently underwent left total parotidectomy.

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“…Following intravenous contrast medium injection at CT and MRI, the lesions may exhibit either homogeneous or inhomogeneous enhancement. They are usually depicted in the superficial lobe of the parotid gland and less frequently found in the deep lobe or the tail of the gland [50][51][52].…”

Section: Reviewmentioning

confidence: 99%

Malignant Myoepithelioma of the Parotid Gland: Literature Review on the Occasion of Our Report of a Case

Kyrgias¹,

Kalogeridi²,

Tzitzikas³

et al. 2012

IJCM

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Malignant myoepitheliomas are rare malignant salivary gland neoplasms which usually occur in the parotid gland. Very little material on this topic has been published. This tumour represents a therapeutic challenge since there are no specific recommendations or guidelines. We present a case of malignant myoepithelioma arising de novo in the parotid gland. We discuss our therapeutic approach and considerations on appropriate post-surgical treatment. Then we provide a review of international literature on this interesting and rare oncological entity

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Giant epithelial-myoepithelial carcinoma of the parotid gland

Cited by 10 publications

References 10 publications

A Rare Case of Clear Cell Carcinoma of the Parotid Gland in Iran

A Rare Case of Clear Cell Carcinoma of the Parotid Gland in Iran

Epithelial-Myoepithelial Carcinoma of Salivary Glands

Malignant Myoepithelioma of the Parotid Gland: Literature Review on the Occasion of Our Report of a Case

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