Giant duodenal Brunner’s gland hamartoma successfully treated via endoscopic mucosal resection

Kitagawa, Yusuke; Osumi, Hiroki; Kawachi, Hiroshi; Yoshio, Toshiyuki; Yoshimizu, Shoichi; Horiuchi, Yusuke; Ishiyama, Akiyoshi; Hirasawa, Toshiaki; Tsuchida, Takaaki

doi:10.1016/j.ajg.2018.08.004

Cited by 9 publications

(14 citation statements)

References 5 publications

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“…Endoscopic treatments for large Brunner’s hamartomas with relatively low complication and mortality rates is effective and safe [5, 6]. But not all the large BGH could be removed endoscopically.…”

Section: Discussionmentioning

confidence: 99%

“…Brunner’s gland hamartoma can be treated either by endoscopic or surgical excision [4]. To our knowledge, up to now, only 4 cases of endoscopic resection of BGH larger than 7 cm have been reported [5–8]. In two cases, the BGH was removed by endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR) respectively [5, 6].…”

Section: Introductionmentioning

confidence: 99%

“…To our knowledge, up to now, only 4 cases of endoscopic resection of BGH larger than 7 cm have been reported [5–8]. In two cases, the BGH was removed by endoscopic submucosal dissection (ESD) and endoscopic mucosal resection (EMR) respectively [5, 6]. In the other two cases being reported 13 years and 18 years ago respectively, neither of them pretreated the stalk, which was very important to the strategy for the treatment of pedunculated mass, to prevent the main adverse event post-polypectomy bleeding (PPB) [7, 8].…”

Section: Introductionmentioning

confidence: 99%

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A giant Brunner’s gland hamartoma being treated as a pedunculated polyp: a case report

Cheng

Qiu

et al. 2019

BMC Gastroenterol

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Background With the development and application of endoscopic technology, most pedunculated polyps can be absolutely resected with a complete specimen by hot snare polypectomy (HSP). Brunner’s gland hamartoma (BGH) is a rare benign small bowel tumor. The majority of BGH measuring about 2 cm in diameter, rarely larger than 5 cm. Most patients are asymptomatic, some may present with gastrointestinal hemorrhage or intestinal obstruction. Symptomatic larger lesions leading to bleeding or obstruction should be excised either endoscopically or surgically. Whether it is safe and effective that removing a BGH measuring about 7 cm by HSP is not known. Case presentation Here, we reported a rare case of a proximal duodenum pedunculated mass measuring about 7 cm which was responsible for the patient’s severe anemia. we treated it as a pedunculated polyp. After being pretreated the stalk with an endoloop which was placed around the base of the mass to prevent post-polypectomy bleeding (PPB), the pedunculated BGH was removed by HSP completely. The stalk of the mass was negative. We achieved a curative resection. Conclusion It is a safe and effective for our patient to treat the pedunculated BGH measuring about 7 cm as a pedunculated polyp and remove it by HSP. And future prospective studies in larger cohorts are needed to confirm it.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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A giant Brunner’s gland hamartoma being treated as a pedunculated polyp: a case report

Cheng

Qiu

et al. 2019

BMC Gastroenterol

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“…On gross pathology (Fig. 2 ), Brunner’s gland hamartoma is generally characterized by a solid mass with well-defined boundary, smooth surface covered by normal duodenal mucosa, pink or tawny cut surface, lobules separated by fibrous septa, and internal cystic changes [ 6 , 42 ]. Microscopically (Fig.…”

Section: Diagnostic Approachesmentioning

confidence: 99%

Brunner’s Gland Hamartoma of the Duodenum: A Literature Review

Zhu

et al. 2021

Adv Ther

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Brunner's gland hamartoma is a benign tumor of the duodenum, but has malignant potential with a very low risk of progression into adenocarcinoma. It is uncommon with a frequency of less than 1.0% among the primary tumors of the small intestine. In addition, its clinical manifestations are nonspecific, etiology remains unclear, and treatment strategy needs to be further refined. This literature review mainly discusses the epidemiology, clinical features, possible etiology and pathogenesis, diagnostic methods, malignant potential, treatment, and prognosis of Brunner's gland hamartoma.

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“…2,4 Mostly they are asymptomatic or present with chronic abdominal pain, nausea, vomiting, gastrointestinal bleedings, and anemia. 5 We are reporting a rare case and eldest case of BGA presented with upper gastrointestinal bleeding.…”

Section: Introductionmentioning

confidence: 98%

Giant Brunner’s Gland Adenoma Presenting as Upper Gastrointestinal Bleeding in 76 Years Old Male: A Case Report

Rana¹,

Sapkota²,

Kc³

et al. 2019

J Nepal Med Assoc

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Brunner’s gland adenoma is a rare benign tumor of small bowel, often incidentally discovered during endoscopy or radiological imaging. Mostly they are asymptomatic or often present with nonspecific symptoms such as nausea, vomiting, gastrointestinal hemorrhage, iron deficiency anemia. We reported a 76 years old male case presented with chief complaints of vomiting and black tarry stool. General physical examination was normal except mild tenderness over epigastrium. Esophagogastroduodenoscopy revealed a pedunculated polypoid tubular structure with blind end distally of length approximately 10-12* 3.5*1.5 cm in the second section of the duodenum with multiple skipped ulcers on the exposed surface of it. Additionally, there were few erosions in the duodenum proximally and multiple superficial ulcerations in the antrum, associated with helicobacter pylori confirmed by rapid urease test kit. Keywords: Brunner’s gland adenoma; Brunner’s gland hamartoma; Brunner’s gland hyperplasia; case report.

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Giant duodenal Brunner’s gland hamartoma successfully treated via endoscopic mucosal resection

Cited by 9 publications

References 5 publications

A giant Brunner’s gland hamartoma being treated as a pedunculated polyp: a case report

A giant Brunner’s gland hamartoma being treated as a pedunculated polyp: a case report

Brunner’s Gland Hamartoma of the Duodenum: A Literature Review

Giant Brunner’s Gland Adenoma Presenting as Upper Gastrointestinal Bleeding in 76 Years Old Male: A Case Report

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