“…Even though cutaneous horn is a relatively uncommon entity, different cases have been described. For example, Bo Lin et al wrote about a giant cutaneous horn on the cheek in a 83-year-old woman with an 18-year history of growth [ 1 ], Oded Nahlieli et al reported four cases occurring in the head and neck region [ 13 ], G. N. Purohit et al presented a case of a cutaneous horn following injury to pinna in a 55-year-old male farmer [ 14 ], William Leppard et al reported a case of a giant cutaneous horn of the scalp in a 52-years-old African American female [ 15 ], Michal et al described four cases of gigantic cutaneous horns of the scalp [ 16 ] and K. K. Sanjeeva et al presented a giant cutaneous horn overlying a verruca over the left gluteal region in a 64-year-old man [ 17 ]. Despite this, no one has ever focused on the causes that have allowed such an important growth of these lesions.…”