Giant congenital melanocytic nevus scalp: report of a rare case

Abstract

Giant congenital melanocytic nevus (garment nevus) is a kind of congenital malformation of neural crest cells with size greater than 20 cm. Malignant melanoma may develop in 2-31% of these lesions. The objective of this paper is to present a unique case of giant nevus which is rare. [Int J Res Med Sci 2013; 1(3.000): 317-319

Giant cerebriform melanocytic nevus of the scalp: A case report

“…The size of CMN is extremely important since it increases the risk of malignancy transformation and is a decisive factor in cosmetic and therapeutic approaches. 9 Giant congenital melanocytic nevi are mostly characterized as brownish lesions with distinct borders and hypertrichosis. In comparison with acquired melanocytic nevi, CMN have a heterogeneous morphology and they're larger in size.…”

“…Head and neck lesions are less common (14%). 9,10 In histologic examination, epidermal changes of CMN are similar to acquired melanocytic nevi however they can be distinguished by the presence of nevus cells in the deep dermis and subcutaneous tissue; arrangement of these cells among the collagen bundles of the lower reticular dermis; the involvement of sebaceous glands, blood vessels, erector muscles of hair follicles, eccrine glands and lymphatic vessels. 6 A major concern about CMN is malignant transformation to melanoma which can develop within the nevus or elsewhere, especially the central nervous system.…”

“…Based on their size in greatest diameter, CMN are categorized into three groups: small (<1.5 cm), medium (1.5‐19.9 cm), and large or giant (≥20 cm). The size of CMN is extremely important since it increases the risk of malignancy transformation and is a decisive factor in cosmetic and therapeutic approaches 9 …”

Giant Cerebriform Melanocytic Nevus of the Scalp; A Case report

“…Head and neck lesions are less common (14 %). (9,10) In histologic examination, epidermal changes of CMN are similar to acquired melanocytic nevi however they cab be distinguished by the presence of nevus cells in the deep dermis and subcutaneous tissue; arrangement of these cells among the collagen bundles of the lower reticular dermis; the involvement of sebaceous glands, blood vessels, erector muscles of hair follicles, eccrine glands and lymphatic vessels. 6A major concern about CMN is malignant transformation to melanoma which can develop within the nevus or elsewhere, especially the central nervous system.…”

Insight into evolution of a giant congenital nevomelanocytic nevus over 14 years

“…Multiple small satellite nevi may be present either at birth or during early childhood (tardive satellite). [1,3] The follow-up of giant congenital nevomelanocytic nevi is important because of their tendency toward melanoma transformation. It is estimated that 4.6% of patients with congenital giant nevi are at a risk of developing malignant melanoma.…”