Giant Cervical Parathyroid Adenoma Mimicking a Sternocleidomastoid Mass and Presenting as a Brown Tumor of the Mandible

Desigan, Sharmini; Syed, Rabbani; Conway, Gerard S.; Kurzawinski, Tomasz R.; Bomanji, Jamshed

doi:10.1097/01.rlu.0000257293.00744.3c

Cited by 6 publications

(1 citation statement)

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“…In terms of physical examination, the majority of GPTAs in the neck had a visible and palpable mass in the neck [7, 11, 13, 14, 17, 19, 20, 24, 25]. Their large size is one of the reasons a clinician may suspect thyroid disease before reviewing the laboratory results, as palpable nodules are more common in the thyroid.…”

Section: Discussionmentioning

confidence: 99%

Giant parathyroid adenoma: a case report and review of the literature

et al. 2019

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BackgroundGiant parathyroid adenoma is a rare type of parathyroid adenoma defined as weighing > 3.5 g. They present as primary hyperparathyroidism but with more elevated laboratory findings and more severe clinical presentations due to the larger tissue mass. This is the first reported case of giant parathyroid adenoma from the Middle East.Case presentationA 52-year-old Indian woman presented with a palpable right-sided neck mass and generalized fatigue. Investigations revealed hypercalcemia with elevated parathyroid hormone and an asymptomatic kidney stone. Ultrasound showed a complex nodule with solid and cystic components, and Sestamibi nuclear scan confirmed a giant parathyroid adenoma. Focused surgical neck exploration was done and a giant parathyroid adenoma weighing 7.7 gm was excised.ConclusionsGiant parathyroid adenoma is a rare cause of primary hyperparathyroidism and usually presents symptomatically with high calcium and parathyroid hormone levels. Giant parathyroid adenoma is diagnosed by imaging and laboratory studies. Management is typically surgical, aiming at complete resection. Patients usually recover with no long-term complications or recurrence.

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