Giant Cell Tumour of Tendon Sheath of the Digits. A Systematic Review

Fotiadis, Elias; Papadopoulos, Alexis; Svarnas, Theodoros; Akritopoulos, P.; Sachinis, Nikolaos Platon; Chalidis, Byron

doi:10.1007/s11552-011-9341-9

Cited by 62 publications

(84 citation statements)

References 20 publications

(158 reference statements)

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“…Consistent with our study, Darwish et al observe a slight predominance of the right hand [4]. Some authors report that the most frequent tumor location is the index finger [6,8,9]. Darwish et al, however, report that the most common location of the tumor is the thumb [4].…”

Section: Discussionsupporting

confidence: 90%

Localized Giant Cell Tumors of the Flexor Tendon Sheath of the Finger: An Analysis of Twenty Five Patients

Sayit¹,

Sayıt²,

İdilman³

et al. 2016

Ann Clin Anal Med

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Anahtar KelimelerDev Hücreli Tendon Kılıfı Tümörleri; Parmak; MR Görüntüleme; Cerrahi; Direk Grafi Abstract Aim: The aims of this retrospective study were to evaluate localized giant cell tumors of the tendon sheath (GCTTS) with Magnetic Resonance (MR) imaging findings and to review the epidemiological features of the disease. We also evaluated the literature regarding GCTTS and performed an analysis of the available information. Material and Method: We retrospectively reviewed the MR images of 25 histologically proven cases of GCTTS of the finger during the period between 2012-2014. In addition, a retrospective analysis of the patients' records was carried out, and age, gender, site and size of lesion, recurrence, and MRI findings were reviewed. Results: The patients were predominantly female (n = 16) and had a mean age of 51.9 ± 12.8 years. Nine patients were male with a mean age of 45.1 ± 13.4 years. The size of the tumors ranged from 6 mm to 30 mm, with a mean size of 15.3±6.8 mm. Tumors were present on the right hand in 15 patients and on the left hand in 10 patients. Among women, 11 tumors were located on the right hand and 5 were found on the left. In men, 4 of the tumors were located on the right hand and 5 were on the left. The most frequent digit on which tumors were found was the index finger, accounting for 40% of cases (n=10). The most frequent location was the index finger for both women (n=6) and men (n=4). All of the lesions were described as well-circumscribed, encapsulated, lobulated, or multilobulated solitary masses with MR imaging. Signal intensity on T1 weighted images (WI) was equal to that of skeletal muscle in 23 cases. In two cases, signal intensity was slightly higher. On T2WIs, the signal intensities tended to be between those of skeletal muscle and fat in all of the cases. All of the lesions showed mild to moderate contrast enhancement when compared with precontrast images. There was no statistically significant differences between male and female patients in terms of age, tumor side, involved digit, and highest tumor size. But, tumor volume was slightly larger in female patients compared with male patients (p= 0.083). Discussion: MR imaging is very valuable in the diagnosis of GCTTS because of characteristic internal signal intensity. Also, axial and sagittal images are useful for evaluating the degree of extension around the phalanx, and invasion into the joint and tenosynovial space prior to surgery. These factors can influence the surgical approach.

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Section: Discussionsupporting

confidence: 90%

Localized Giant Cell Tumors of the Flexor Tendon Sheath of the Finger: An Analysis of Twenty Five Patients

Sayit¹,

Sayıt²,

İdilman³

et al. 2016

Ann Clin Anal Med

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“…Our results are consistent with most prior research that states that GCTTS is more frequently seen in female patients on the volar side of the hand. The distribution of GCTTS by finger was also comparable with previous research, with the index finger as the most prevalent location (2,9,14). We were unable to find other studies that have tried to identify factors associated with the increased size of a GCTTS.…”

Section: Discussionsupporting

confidence: 84%

“…Current studies are limited to small retrospective series with a varying range (44-74%) of results for location (volar versus dorsal side) (7,(10)(11)(12)(13). A recent systematic review by Fotiadis et al did not look into volar versus dorsal location of GCTTS on digits (2). This study includes a relatively large series of patients.…”

Section: Discussionmentioning

confidence: 99%

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Giant Cell Tumor of the Tendon Sheath

小山田¹,

北島²,

米田³

et al. 2011

Imaging of Pain

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IntroductionG iant cell tumor of tendon sheath (GCTTS) and ganglion cyst are the most common benign tumors of the hand (1, 2). In general GCTTS can present as a solitary subcutaneous nodule of the hand, but it can also occur in other parts of the body such as the spine, ankle, knee and feet (3, 4). However, with an approximate incidence of 1/50,000 per population it remains an uncommon condition (5). The incidence of GCTTS is higher in women than in men and mostly seen in the third to fifth decade (3, 6).The results of previous research are inconsistent regarding whether GCTTS is more often volar or dorsal in the hand, with a tendency for it to occur more often on the volar aspect of the hand (7-10). The occurrence of a volarsided GCTTS has been reported to range between 44 and 76% (7-11). The purpose of this study was to examine a large series of GCTTS in the hand to further assess the relative frequency of dorsal and volar GCTTS. We hypothesized that GCTTS are equally common on the dorsal and volar aspects of the hand. In addition, we hypothesized that there are no factors (i.e., demographic, clinical and pathological) associated with the location (volar versus dorsal side) and largest measured diameter of a GCTTS. Materials and MethodsUnder an IRB approved protocol 278 patients that had operative treatment of a GCTTS between January 2002 and November 2012 were identified using a database of pathology reports. The study was performed in a single tertiary care hospital and the procedures were performed by four experienced hand surgeons. Informed consent was waived for this medical record study. The medical records of all patients aged 18 years or older with a pathologically confirmed GCTTS of the finger or hand were reviewed retrospectively. Pregnant women (IRB mandated) and patients with a recurrence of a GCTTS already surgically treated in our center were excluded. We recorded sex, age, side, dorsal or volar location, finger or hand location and largest measured diameter of the GCTTS. The diameter was obtained from the pathology report. Giant Cell Tumor of Tendon SheathAbstract Background: Giant cell tumor of tendon sheath (GCTTS) is often thought of as a volar finger mass. We hypothesized that GCTTS are equally common on the dorsal and volar aspects of the hand. In addition, we hypothesized that there are no factors associated with the location (volar versus dorsal) and largest measured dimension of a GCTTS.

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“…1 Generally, it presents itself as a subcutaneous nodule over the hand, but occasionally it may involve other parts of the body as well, such as the spine, ankle, knee and feet. 2 Overall incidence in general populations is 1/50,000.…”

Section: Introductionmentioning

confidence: 99%

Giant cell tumor of tendon sheath

et al. 2017

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Giant Cell Tumor of Tendon Sheath (GCTTS) is the second most common benign tumour affecting hand after ganglion. The tumor generally affects individuals between the age of 30 and 50 years, and is found more often in women than men. The etiological factors responsible for GCTTS are unclear. Some authors consider it as an inflammatory process arising as a consequence of chronic antigenic stimulation. Local excision with or without radiotherapy is the treatment of choice. We recently encountered two cases of Giant cell tumor involving tendon sheath of ring finger in one case and thumb in another case. Both were managed surgically with good results. There has been no evidence of recurrence till date in the follow up varying from 3-6 months.

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Giant Cell Tumour of Tendon Sheath of the Digits. A Systematic Review

Cited by 62 publications

References 20 publications

Localized Giant Cell Tumors of the Flexor Tendon Sheath of the Finger: An Analysis of Twenty Five Patients

Localized Giant Cell Tumors of the Flexor Tendon Sheath of the Finger: An Analysis of Twenty Five Patients

Giant Cell Tumor of the Tendon Sheath

Giant cell tumor of tendon sheath

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