Giant cell tumour of tendon sheath and synovial membrane: A review of 26 cases

Abstract

Meticulous en-masse marginal excision of the giant cell tumour of tendon sheath in blood less field using magnification is the treatment of choice.

A rare localized giant cell tumor of the tendon sheath originating from the ligamentum mucosum: A case report

“…Although there are many treatment modalities for GCTTS, marginal excision is the most commonly used. [2] Arthroscopic or open excision of GCTTS in the knee joint has been described in previous studies. [4,5] Open surgery allows adequate marginal excision of surrounding tissues that may have been invaded by the tumor and, therefore, exhibits a decreased risk of local recurrence when compared with arthroscopic surgery.…”

“…In addition, hemosiderin (brown color) may be present but typically less than is seen in PVNS, and multinucleated giant cells are common. [2,3,13] Differential diagnosis includes ganglion cyst, PVNS, or fibromas. [1,13] Pigmented villonodular synovitis is histologically identical with GCTTS but it most commonly involves the whole synovium in larger joints and pronounced hemosiderin, which produces a characteristic signal on MRI.…”

“…Recurrence is the most frequent complication for both localized (GCTTS) and diffuse (diffuse PVNS) tumors. [1][2][3] The local recurrence rate has been reported to be between 4-45% in most cases; however, only a few studies have been conducted. [4,5,10] Loriaut et al [10] published a study involving 30 patients with localized PVNS of the knee who were treated arthroscopically and found that only four patients had recurrence at a mean 75-month follow-up.…”

“…Giant cell tumor of the tendon sheath (GCTTS) and synovium mainly occurs in two forms, including localized GCTTS and diffuse pigmented villonodular synovitis (PVNS). [1][2][3] Giant cell tumor of the tendon sheath generally affects the small joints in the extremities and usually presents as a solitary soft tissue mass, but involvement of the major joints has recently become more prevalent. [4,5] To date, a number of cases of GCTTS in the knee joint have been reported in the literature that describe GCTTS originating in the anterior cruciate ligament (ACL), [6] posterior cruciate ligament (PCL), [7] patellar tendon, [8] and medial plica.…”

A Pregnant Woman with Multi-Fragmented Giant Cell Tumor of Tendon Sheath: A Rare Anatomical Location

“…4,5 It can be seen at any age but mostly affects individuals in their third to fifth decades of life and is mostly seen in females. [6][7][8] GCTTS has not previously been reported in a pregnant woman. Etiology of GCTTS is not clear but there are many risk factors mentioned in the literature such as trauma, infection, vascular abnormality, lipid metabolism disorders, osteoclastic proliferation, and immune system disorders.…”