Giant cell tumour of clavicle: Occurrence of a common tumour in a rare location

Khatri, Kavin; Singh, Jagdeep; Kalia, Anoop; Dahuja, Anshul

doi:10.1016/j.ijscr.2016.10.052

Cited by 6 publications

(4 citation statements)

References 6 publications

(7 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…GCT of the clavicle is rare with only 15 cases reported in literature in the last 40 years[ 3 4 6 7 8 9 10 11 12 13 14 15 ] [ Table 1 ]. Out of these, 7/15 were male and 8/15 were female.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Giant cell tumor of clavicle in an elderly: Rare presentation of a common tumor with review of literature; 1980–2020

Garg

Tanveer

et al. 2021

J Microsc Ultrastruct

View full text Add to dashboard Cite

Giant cell tumor (GCT), also known as osteoclastoma, is a locally aggressive benign tumor arising in the epiphysis of bone. It accounts for 3%–8% of all bone tumors. About 75%–90% of GCTs occur in long tubular bones with more than 50% arising in the distal femur and proximal tibia. Flat bone involvements such as ribs, skull, patella, sternum, and clavicle are rare. Sixty–seventy percent of patients with GCT are between 20 and 40 years of age, rarely affecting too young or too old. We present here an unusual case of GCT of the clavicle in a 62-year-old female.

show abstract

“…GCT of the clavicle is rare with only 15 cases reported in literature in the last 40 years[ 3 4 6 7 8 9 10 11 12 13 14 15 ] [ Table 1 ]. Out of these, 7/15 were male and 8/15 were female.…”

Section: Discussionmentioning

confidence: 99%

“…[ 6 14 ] On postsurgical resection, there was no recurrence or metastasis over 1 year of follow-up in these three cases. [ 6 12 14 ]…”

Section: Discussionmentioning

confidence: 99%

Giant cell tumor of clavicle in an elderly: Rare presentation of a common tumor with review of literature; 1980–2020

Garg

Tanveer

et al. 2021

J Microsc Ultrastruct

View full text Add to dashboard Cite

show abstract

“…Limited case reports or case series are currently available that provide information on these tumors. 1,2 The majority of primary clavicle tumors are malignant 3,4 and surgical treatment entails partial or total clavicle excision based on the disease extent. 5 Approximately 1.4% of all cases of Ewing's sarcoma occur in the clavicle.…”

Section: Introductionmentioning

confidence: 99%

Functional and Oncological Outcomes of Multidisciplinary Management of Ewing’s Sarcoma of Clavicle: A Single-Center Experience

Gulia

Puri

Gupta

et al. 2021

South Asian J Cancer

View full text Add to dashboard Cite

Objectives Ewing’s sarcoma is best treated using a multidisciplinary approach. We discuss the functional and oncological outcomes of clavicular Ewing’s sarcoma which has been sparsely reported in literature. Materials and Methods We retrospectively evaluated patients who underwent resections for Ewing’s sarcoma of clavicle from January 2002 to December 2017. The study end points were locoregional recurrence free survival (LRFS), disease-free survival (DFS), and overall survival (OS) at 3 and 5 years, and functional outcomes measured by Musculoskeletal Tumor Society (MSTS) scores. Statistical Analysis The LRFS, DFS, and OS were calculated and analyzed using the Kaplan–Meier method and log-rank test. Results Data of 21 patients (male: 12, female: 9) was analyzed with a mean age [range] of 15.3 [6–40] years. Total clavicle excision was done in 62% (13 of 21) while 38% (n = 8) had partial resections. Radiotherapy was administered in 15 patients (71.5%). At a median follow-up of 42 months (range: 7–198), data of 20 patients was available for follow-up. Ten patients died (due to disease: nine, other reasons: One), eight are disease free and alive, one had metastasectomy on recurrence and is disease free and, one patient is alive with disease and on palliative chemotherapy. The LRFS, DFS, and OS were 95, 59, 65% and 95, 47, 59% at 3 and 5 years, respectively. The functional evaluation done for nine patients who are free of disease showed a mean MSTS score of 29 (range: 27–30; total clavicle excision: 28.5, partial clavicle excision: 29.5). Conclusion Patients with Ewing’s sarcoma of the clavicle who underwent resection without reconstruction have acceptable local control rates and excellent functional outcomes.

show abstract

“…Bone tumours of the clavicle are exceedingly rare with a reported frequency of less than 1% of all bone tumours [1], [2]. There is a paucity of literature focusing on these lesions with most of the published articles being case reports or small case series [1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14]. Hence, the majority of physicians have limited experience in the diagnosis and treatment of these lesions.…”

Section: Introductionmentioning

confidence: 99%

Bone tumours of the clavicle: Histopathological, anatomical and epidemiological analysis of 113 cases

Priemel

Stiel

Zustin

et al. 2019

Journal of Bone Oncology

View full text Add to dashboard Cite

Backround This retrospective study aimed to determine the frequency of bone tumours of the clavicle and their histopathological, anatomical and epidemiological characteristics in a large case series. Methods The records of 327 lesions of the clavicle collected from 1976 to 2018 in our bone tumour registry and institute of pathology were reviewed. Following data were evaluated: age, gender, side, radiological assessment, tumour location within the clavicle, and histopathological findings. Results Bone tumours were detected in 113 patients with a mean age of 40 years. The lateral third of the clavicle was most frequently involved. Analysis revealed 22 benign, 31 intermediate, and 60 malignant tumours. Eosinophilic granuloma was the most commonly found neoplasm (18.6%), followed by bone metastases (15.0%), Plasma cell myeloma (8.8%), Ewing sarcoma (8.8%), and Osteosarcoma (8.0%). 53% of the tumours were malignant. Mean age was 51 years in the malignant tumour group and 28 years in patients with a benign/intermediate lesion ( p < 0.001). Conclusions The high incidence of malignant bone tumours of the clavicle found in this study highlight the importance of biopsy to prevent delay in diagnosis and treatment of these lesions, especially in patients with increased age. We believe that the results of this study are of clinical importance and may aid the physician in the management of these rare lesions.

show abstract

Giant cell tumour of clavicle: Occurrence of a common tumour in a rare location

Cited by 6 publications

References 6 publications

Giant cell tumor of clavicle in an elderly: Rare presentation of a common tumor with review of literature; 1980–2020

Giant cell tumor of clavicle in an elderly: Rare presentation of a common tumor with review of literature; 1980–2020

Functional and Oncological Outcomes of Multidisciplinary Management of Ewing’s Sarcoma of Clavicle: A Single-Center Experience

Bone tumours of the clavicle: Histopathological, anatomical and epidemiological analysis of 113 cases

Contact Info

Product

Resources

About