Giant cell tumors of the bones of the hand

Athanasian, Edward A.; Wold, Lester E.; Amadio, Peter C.

doi:10.1016/s0363-5023(05)80187-x

Cited by 124 publications

(157 citation statements)

References 9 publications

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“…This feature was also present in the Mayo Clinic series. 7,19 This concept was also underlined by Dorfman and Czerniak. 8 Lung metastases were not reported in our series of GCT of the small bones of the hand and foot.…”

mentioning

confidence: 87%

Giant cell tumor of the bones of the hand and foot

Biscaglia

Bacchini

Bertoni

2000

Cancer

130

112

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mentioning

confidence: 87%

Giant cell tumor of the bones of the hand and foot

Biscaglia

Bacchini

Bertoni

2000

Cancer

130

112

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“…2,4 It is rare in the small bones of the hands and feet (between 1.7% and 5% of all GCTs). [5][6][7][8][9][10][11] The differential diagnosis includes enchondroma, fibrous dysplasia, aneurysmal bone cyst, osteomyelitis and brown tumour from hyperparathyroidism.…”

mentioning

confidence: 99%

“…[6][7][8]17 Most recurrences occur within two years of surgery, and en bloc resection has been shown to result in a lower rate of recurrence (0% to 50%). [6][7][8]18,19 However, reconstruction after resection may be difficult in cases of multicentric GCT of the small bones, which has been reported in 7% to 18% of cases. 5,20 Curettage without adjuvants may not afford complete tumour removal, resulting in a higher rate of recurrence (0% to 100%).…”

mentioning

confidence: 99%

“…5,20 Curettage without adjuvants may not afford complete tumour removal, resulting in a higher rate of recurrence (0% to 100%). 6,8,17,21,22 Radiation-induced sarcoma has been reported in 5% to 10% of patients receiving radiotherapy as adjuvant treatment, and it is therefore not recommended for primary lesions. 4,8 The aims of this multicentre study were first to perform a systematic literature review of the surgical treatment of GCT of the small bones.…”

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confidence: 99%

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Giant cell tumours of the small bones of the hands and feet

Oliveira

Heijden

Geest

et al. 2013

The Bone & Joint Journal

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Giant cell tumours (GCTs) of the small bones of the hands and feet are rare. Small case series have been published but there is no consensus about ideal treatment. We performed a systematic review, initially screening 775 titles, and included 12 papers comprising 91 patients with GCT of the small bones of the hands and feet. The rate of recurrence across these publications was found to be 72% ( Giant cell tumour (GCT) is a relatively common benign lytic lesion that accounts for 4% to 5% of primary bone tumours and almost 20% of benign bone tumours. 1 It occurs mainly between the ages of 30 and 50 years and is slightly more common in women. 2,3The most common sites are the meta-epiphyseal regions of the long bones (85%), with more than 50% located in the distal femur, proximal tibia and distal radius.

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“…For aggressive benign bone tumors such as giant cell tumor, the use of adjuvants with curettage has been recommended. [19] However, for giant cell tumors in the finger, amputation may be necessary. [20] For benign bone lesions in general, the curettage site should be checked intraoperatively with radiographs to rule out any residual tumor.…”

Section: Treatmentmentioning

confidence: 99%