Giant Cell Tumor of the Frontal Bone in an 18-Month-Old Girl: A Case Report

Abstract

Although rare, GCTs should be taken into consideration as a differential diagnosis of rapidly enlarging cranial mass lesions in pediatric patients. Gross total surgical excision eliminates the potential risks of adjuvant radiotherapy. However, considering the aggressive nature and potential malignancy of these lesions, careful long-term clinical and imaging follow-up is recommended.

Giant cell tumour of the posterior cranial fossa: a case report

“…It is unclear as to whether the radiotherapy was ultimately necessary. Two cases involving the cranial vault, documented by Coumbaras et al [15] and Ulu et al [16], employed no post-operative radiotherapy and no recurrence was observed during the follow-up period.…”

Giant Cell Tumor of the Frontal Bone Presenting as an Orbital Mass

“…Indeed, Kamoshima et al described a 2-year-old female patient with recurrent GCT of the frontal bone that underwent two partial surgical removals of the tumor with recurrence before total resection of the lesion, surrounding bone, and frontal base dura mater was curative [14]. The reported incidence in the literature of non-recurrence after total resection of a frontal bone lesion has been up to 30 months [15]. If total resection cannot be achieved, the combination of subtotal resection and radiation therapy shows a similar low recurrence.…”

Giant cell tumor of the frontal sinus: case report

“…4 In the English literature, only three cases reported of such tumor involving the frontal bone in adults and one pediatric patient. [5][6][7] Only one of these cases was filling the frontal sinus. Hlavácek et al described their first 2 cases report of frontal giant cell tumor as a polyostotic form of the disease.…”

“…There are only 3 cases reported in the English literature as a GCT of frontal bone in adult patients and 1 pediatric patient. [5][6][7] Only one of them was a frontal sinus occupying mass. 5 None of these case reports included a complete clinical, radiological and histopathological demonstration.…”