Giant cell tumor of the tendon sheath of the toe: case report of an unusual localization

Giant cell tumor of tendon sheath in the pediatric population – review

“…Interphalangeal joints are often affected [13]. It may also be found in foot (with tendency to be spotted in forefoot), ankle, knee, hip, elbow or shoulder, although location in large joints or the spine is rare [2,4]. This tumor can be divided into two types: intra-articular or extra-articular [7].…”

“…This tumor can be divided into two types: intra-articular or extra-articular [7]. GCTTS may be described as localized tumor, which tends to be a benign form, and diffuse form, which appears to be more aggressive and more likely to localize in large joins [4]. Local and diffuse forms are morphologically ndistinguishable, however location near large joints or local agressiveness are more characteristic for the diffuse form [13].…”

“…Giant cell tumor of tendon sheath (GCTTS), also known as tenosynovial giant cell tumor, is the most frequent form of giant cell tumors and the second most common soft tissue tumor of the hand (after ganglion cyst) [1][2][3]. GCTTS is most often localized in the hands [4]. This tumor originates from the sheath, bursa or joints [2,[5][6].…”

“…This tumor originates from the sheath, bursa or joints [2,[5][6]. Tumor is typically benign, but with aggressive or malignant potential [2,4]. GCTTS may occur as localized or diffuse form [7][8] and is most common among adults 30 to 50 years of age.…”

“…GCTTS may occur as localized or diffuse form [7][8] and is most common among adults 30 to 50 years of age. [2,4,7,[9][10]. The global incidence rate of GCTTS located in the digits, limb and the diffuse-type are respectively 29, 10, and 4 per million person-years [11].…”