Giant cell reparative granuloma of the temporal bone successfully resected with preservation of hearing

Takata, Yusuke; Hidaka, Hiroshi; Ishida, Kazuyuki; Kobayashi, Tomoko

doi:10.1017/s002221511300114x

Cited by 6 publications

(3 citation statements)

References 15 publications

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“…Giant-cell reparative granulomas have been located in the anterior temporal bone (squamous part); that is, above the temporomandibular joint. Therefore, we considered this location to be a characteristic of giant-cell reparative granulomas [ 22 , 26 , 27 , 28 , 29 , 30 ]. Giant-cell reparative granulomas have expansile lesions with bone remodeling and thinning of the surrounding bone [ 23 ] ( Figure 5 ).…”

Section: Reviewmentioning

confidence: 99%

Imaging of Temporal Bone Mass Lesions: A Pictorial Review

et al. 2023

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Tumoral lesions of the temporal bone include benign or malignant tumors and congenital or inflammatory lesions. Temporal bone lesions are difficult to approach. Therefore, making a preoperative diagnosis and considering whether the lesions require treatment are necessary; if they require treatment, then the type of treatment requires consideration. These tumors cannot be observed directly and must be diagnosed based on symptoms and imaging findings. However, the differentiation of temporal bone lesions is difficult because they are rare and large in variety. In this pictorial review, we divided temporal bone lesions by location such as along the facial nerve, along the internal jugular vein, around the endolymphatic sac, in the internal auditory canal/cerebellopontine angle, petrous apex, middle ear, and mastoid, focusing on the imaging findings of temporal bone lesions. Then, we created a diagnostic flowchart that suggested that the systematic separation of imaging findings is useful for differentiation. Although it is necessary to make comprehensive judgments based on the clinical symptoms, patient background, and imaging findings to diagnose temporal bone mass lesions, capturing imaging features can be a useful differentiation method.

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Section: Reviewmentioning

confidence: 99%

Imaging of Temporal Bone Mass Lesions: A Pictorial Review

et al. 2023

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“…Several writers have addressed the toxicity and biological impacts of mycotoxins in foods [19] [20] [21] (Table 3).…”

Section: Toxic Effects Of Mycotoxins On Healthmentioning

confidence: 99%

Mycotoxin’s Infections and Prevention Methods: State of the Art

Viviane¹,

Masabo²,

Habiyaremye³

et al. 2021

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“…First described by Jaffe in 1953 (1), central giant cell granuloma (CGCG) is a very rare intraosseous benign lesion typically of the jaws, however more frequently occurring in the mandible than in the maxilla (2,3). Other regions like the skull base, ethmoid sinus or temporal bone are far less affected, respectively only reported in individual cases (4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19). The incidence of CGCG is reported with 1.1 to 1.97 per 10 6 (20,21) and a slightly higher frequency in females than males (1.25 vs. 1.05 per 10 6 ) (21).…”

Section: Introductionmentioning

confidence: 99%

Central giant cell granuloma of the temporal bone and temporo-mandibular-joint: a case report

Roth¹,

Meier²,

Ettl³

et al. 2022

Front Oral Maxillofac Med

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We present a seldom case of a patient with extended central giant cell granuloma (CGCG) of the temporal bone and temporomandibular joint representing a detailed example of diagnostical procedures, surgical approach, histological differentiation, treatment options and follow-up. In general, CGCG is a very rare benign osseous lesion of the jaws, more frequently occurring in the mandible than the maxilla. Other regions, such as skull base, ethmoid sinus or temporal bone, are far less common and only seldomly reported.Patients are usually younger than 30 years with a slightly higher occurrence rate in females than males.CGCG usually presents as unspecific incidental radiological finding or with unspecific clinical symptoms, e.g., indolent swelling. Lesions can show aggressive behaviour. Its aetiology remains unclear, syndromic occurrence is reported. Final diagnosis of CGCG is based on histopathological and molecular findings but remains difficult due to numerous differential diagnoses. Surgical therapy is the most common treatment, nevertheless other treatment modalities including several primary and adjuvant drug therapies, e.g., topical injection of steroids, systemic calcitonin, interferon-α, RANKL-inhibitors and tyrosine kinase inhibitors, as well as radiotherapy have been discussed with varying effects. Though, recurrence rates differ widely and range up to 72%. Due to the rarity of CGCG randomized controlled trials are still missing.

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Giant cell reparative granuloma of the temporal bone successfully resected with preservation of hearing

Cited by 6 publications

References 15 publications

Imaging of Temporal Bone Mass Lesions: A Pictorial Review

Imaging of Temporal Bone Mass Lesions: A Pictorial Review

Mycotoxin’s Infections and Prevention Methods: State of the Art

Central giant cell granuloma of the temporal bone and temporo-mandibular-joint: a case report

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