Reibel, J.: Oral fibroos hyperplasias containing stellate and multinucleated cells. Scand. J. Dent. Res. 1982: 90: 217-226. Abstract -In an attempt to clarify whether the so-called "giant-cell fibroma" is a separate entity among fibrous hyperplasias and tumors, 1550 oral fibroas hyperplasias were reviewed for the presence of stellate and multinucleated cells. In 5% ofthe lesions stellate and multinucleated cells Wicre a dominant feature of the histologic picture. A surprisingly high number of hyperpiasias of the tuberosities {gingivai fibromatoses) were found to contain the characteristic cells. (31 %). On the basis, ofthe varying nature of the lesions and the range of ages at which the stellate and multinucleated cells are found, these lesions should not be regarded as neoplastic in nature or as belonging to a separate en tit)'. Furthermore, based on differences in fiber pattern and iocalizadon ofthe characteristic cells, it is suggested that the stellate and multinydeated cells are active cells, possibly involved in the synthesis of eoUagen and/or ground substance.