Giant cell arteritis in Asians: a comparative study

Pereira, Luciano S.; Yoon, Michael K.; Hwang, Thomas N.; Hong, Juliette; Ray, Kathyrn; Porco, Travis C.; McCulley, Timothy J.

doi:10.1136/bjo.2009.177220

Cited by 64 publications

(52 citation statements)

References 12 publications

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“…A nationwide survey in 1998 in Japan revealed that the annual incidence rate was 1.47/100,000 people per population aged [50 years, the lowest in the world [6]. This seems due to genetic rather than environmental factors, because GCA occurred less frequently in Asians than in Caucasians [odds ratio (OR) 0.049, 0.0065-0.374, p = 0.03] in the same district in San Francisco [7].…”

Section: Introductionmentioning

confidence: 94%

Role of imaging studies in the diagnosis and evaluation of giant cell arteritis in Japanese: report of eight cases

Morinobu¹,

Tsuji²,

Kasagi³

et al. 2011

Mod Rheumatol

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The objective of this study is to clarify the characteristics and imaging results of Japanese patients with giant cell arteritis (GCA). Eight patients with biopsy-proven GCA were enrolled. Their clinical data and imaging results were retrospectively examined from their medical records. All the patients met the criteria for the classification of GCA by the American College of Rheumatology. Although the clinical manifestations are similar to those previously reported, none of the eight patients presented ocular symptoms, and half of them presented jaw claudication. Ultrasonography (US) of temporal artery showed the halo sign in all the patients. Fluorodeoxyglucose positron emission tomography (FDG-PET) was performed in four patients and indicated the presence of aortitis of the patients. US is a quick and noninvasive test to detect inflammation of temporal artery, and FDG-PET is very helpful for early diagnosis of aortitis in GCA. Awareness of the disease and appropriate imaging tests will result in diagnosis of GCA.

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Section: Introductionmentioning

confidence: 94%

Role of imaging studies in the diagnosis and evaluation of giant cell arteritis in Japanese: report of eight cases

Morinobu¹,

Tsuji²,

Kasagi³

et al. 2011

Mod Rheumatol

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“…GCA and PMR chiefly affect individuals of white (Caucasian) descent 1. The principal risk factor for both diseases is age.…”

Section: Risk Factors For Gca and Pmrmentioning

confidence: 99%

Diagnosis and management of giant cell arteritis and polymyalgia rheumatica: challenges, controversies and practical tips

McDermott

Pease

2013

Postgraduate Medical Journal

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Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR) are inflammatory rheumatic diseases that may present to a variety of disciplines and specialities. The mainstay of treatment is glucocorticoids (steroids); together PMR and GCA now represent one of the most common reasons for medium-to-high dose, long-term glucocorticoid treatment in primary care. However, adverse effects of glucocorticoids are common in these patients. Management of both diseases involves balancing the symptoms and risks of the disease against the adverse effects and risks of glucocorticoids. The crucial first step in management is to make a firm, well-documented diagnosis, since once glucocorticoids are started they can mask the symptoms of a number of other diseases. Diagnosis however can be challenging and there are still substantial gaps in the evidence for treatment.

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“…Au Japon, l'incidence annuelle de l'ACG a été estimée à 1,47/ 100 000 [4] et une étude cas-témoin indique que la fréquence de l'ACG est 20 fois moindre chez les sujets asiatiques vivants aux États-Unis comparativement aux sujets nord-américains issus de population blanche [5]. Toujours aux États-Unis, les afro-améri-cains sont 5 à 7 fois moins touchés par l'ACG que les sujets issus de population blanche [5,6]. L'ACG semble aussi très rare dans des populations hispaniques et arabes [5,7,8].…”

Section: Données éPidémiologiquesunclassified

“…Toujours aux États-Unis, les afro-améri-cains sont 5 à 7 fois moins touchés par l'ACG que les sujets issus de population blanche [5,6]. L'ACG semble aussi très rare dans des populations hispaniques et arabes [5,7,8]. L'ACG ne touche que de manière exceptionnelle les sujets avant l'âge de 50 ans et l'incidence la plus élevée est observée chez des personnes de 70 ans et plus [9].…”

Section: Données éPidémiologiquesunclassified

Artérite à cellules géantes et maladie de Takayasu : aspects épidémiologiques, diagnostiques et thérapeutiques

et al. 2012

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Giant cell arteritis in Asians: a comparative study

Abstract: In our patient population, GCA was seen 20 times less frequently in Asian than Caucasian patients. Although this difference is significantly different (p=0.036), given the small sample size and wide CI this should be viewed as a rough estimate.

Cited by 64 publications

References 12 publications

Role of imaging studies in the diagnosis and evaluation of giant cell arteritis in Japanese: report of eight cases

Role of imaging studies in the diagnosis and evaluation of giant cell arteritis in Japanese: report of eight cases

Diagnosis and management of giant cell arteritis and polymyalgia rheumatica: challenges, controversies and practical tips

Artérite à cellules géantes et maladie de Takayasu : aspects épidémiologiques, diagnostiques et thérapeutiques

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