2002
DOI: 10.1111/j.1444-0938.2002.tb03068.x
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Giant cell arteritis

Abstract: Giant cell arteritis has been considered an enigmatic disease. It is characterised by chronic granulomatous inflammation of the walls of large and medium-sized arteries. The process has a predilection for the extradural cranial arteries, which include the ophthalmic and the posterior ciliary arteries. It is a multi-symptom disease of older individuals and patients often present with challenging issues and diagnostic dilemmas. We review the literature and latest protocols for the diagnosis and management of gia… Show more

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Cited by 8 publications
(3 citation statements)
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“…The pathogenesis of GCA has not been clearly understood. Numerous hypotheses have been proposed, including autoimmune, genetic, environmental, and ischemia-induced destruction of the muscular layers of the artery's tunica media [ 10 ]. Some previous studies suggested that GCA's clinical characteristics are influenced by the autonomic nervous system [ 10 ].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The pathogenesis of GCA has not been clearly understood. Numerous hypotheses have been proposed, including autoimmune, genetic, environmental, and ischemia-induced destruction of the muscular layers of the artery's tunica media [ 10 ]. Some previous studies suggested that GCA's clinical characteristics are influenced by the autonomic nervous system [ 10 ].…”
Section: Discussionmentioning
confidence: 99%
“…Numerous hypotheses have been proposed, including autoimmune, genetic, environmental, and ischemia-induced destruction of the muscular layers of the artery's tunica media [ 10 ]. Some previous studies suggested that GCA's clinical characteristics are influenced by the autonomic nervous system [ 10 ]. There was a case of temporal arteritis with a sympathetic component in the orofacial region [ 11 ].…”
Section: Discussionmentioning
confidence: 99%
“…This may present with impaired vision (optic neuropathy) or impaired motility of the eye (ophthalmoplegia). Isolated optic neuropathy and ophthalmoplegia have been described in almost all forms of systemic vasculitis [43,44], although it is most commonly associated with temporal arteritis [45,46].…”
Section: Optic Neuropathymentioning
confidence: 99%