Giant breast hamartoma in a 41-year-old female: A case report and literature review

Abstract

Abstract. Breast hamartoma is an uncommonly reported benign breast lesion of uncertain cause and pathogenesis. The diagnosis of breast hamartoma by a single method such as mammography, magnetic resonance imaging or sonography is inadequate. In the majority of cases, the breast hamartoma is excised a few years after it has occurred when it is not too big. In the present report, however, a particularly large lesion with a long history is described. Such a case has rarely been reported and shows the necessity of early surgery to reduce trauma as much as possible. Excision of hamartoma was successfully performed and an 11x9x3.5-cm tumor was completely excised. The present study also reviews the literature on breast hamartoma.

Giant mammary hamartoma in a middle aged female. Case report and review of literature of the last 15 years

“…3 ), strongly suggestive a hamartoma. Such an approach that relies on mammogram and ultrasound findings only without the need for additional core biopsy is consistent with other authors ( Table 1 ) who also employed mammogram and ultrasound only, without core biopsy in their diagnosis [ 10 , 13 , 14 , 16 ]. Table 1 also illustrates others who undertook core biopsy after mammogram and ultrasound for four cases of hamartomas, however, the biopsy findings were inconclusive in two of these cases [ 11 , 12 ] whilst the diagnosis was suspected hamartoma in the other two cases [ 15 , 17 ].…”

“…GMH are rarely encountered [ 10 ]. The current hamartoma reached 13 × 11 × 3.7 cm, larger than many other GMH reported in the literature [ [10] , [11] , [12] , [13] , [14] ]. Table 1 depicts GMH > 10 cm, and shows that, globally, the current case represents the fourth GMH in the last 15 years, where only another three hamartomas larger than ours were reported in the literature [ [15] , [16] , [17] ].…”

“…As for recurrence, Table 1 shows that for the reported cases of GMH during the last 15 years, there were no reported recurrences. Others have also observed that recurrence is only occasionally reported and has not been resolved yet [ 13 ].…”

Hamartoma of the breast in a man

“…Although the tumor is histologically benign and often painless, a hamartoma may develop to be quite large if local excision is not performed in a timely manner. [20] Malignancy originating from a hamartoma is extremely rare, but is possible as these tumors contain epithelial tissue. As an example is the case of a 70-year-old woman treated for a mammary hamartoma, who presented with mammogram changes around the mass 6 years later and was diagnosed with invasive ductal carcinoma.…”

Mammary hamartoma: is ultrasound-guided vacuum-assisted breast biopsy sufficient for its treatment?

“…They were mostly soft, round and impalpable masses without any clinical symptoms. Rare giant mammary hamartomas were reported (4,5). Although hamartomas were almost benign lesions, a few rare cases associated with malignant invasive ductal or lobular carcinoma have…”