Giant basal cell carcinoma of the thoracic wall: a case report and review of the literature

Lorenzini, M.; Gatti, Silvia; Giannitrapani, A.

doi:10.1016/j.bjps.2005.04.017

Cited by 36 publications

(51 citation statements)

References 25 publications

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“…[3][4][5][6][7][8][9] Whereas the majority of BCCs are found on the head and neck, 10 most giant lesions are observed at the trunk and other sites covered by clothes. 6,[11][12][13] Reclusive patients are capable of avoiding medical care for these covered lesions for prolonged periods of time, 12-14 even up to 30 years (Table 1). This implies that neglect on the patient's part to seek treatment is the primary reason for BCC to achieve this size, rather than some biologic imperative.…”

Section: Discussionmentioning

confidence: 99%

Super giant basal cell carcinoma of the abdominal wall: still possible in the 21st century

Bree¹,

Laliotis²,

Manios³

et al. 2010

Int J Dermatology

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Basal cell carcinoma (BCC) is very common and usually encountered when it is small in size. Giant BCC (i.e. greater than 5 cm in diameter) is quite rare and comprises 0.5 percent of all BCC. Extremely rarely, tumors larger than 20 cm have been reported. Herein, a case with an enormous, vegetating BCC of the abdominal wall, 30 x 20 cm in size, is described. This report demonstrates that such a case can still be observed in the civilized world of the 21st century, which remains profoundly astonishing. A literature survey was performed and revealed only 7 cases with such super giant BCC (i.e. larger than 20 cm in diameter). Generally, this tumor attains these enormous proportions due to neglect on the patient's part, and is usually located at sites covered by clothes. Treatment is mainly surgical and generally curative, resulting also in an improved quality of life. Tumor size of more than 10 cm in diameter is associated with increased risk for metastatic disease, severe morbidity and consequently impaired prognosis.

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Section: Discussionmentioning

confidence: 99%

Super giant basal cell carcinoma of the abdominal wall: still possible in the 21st century

Bree¹,

Laliotis²,

Manios³

et al. 2010

Int J Dermatology

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“…A split thickness skin graft was placed, and a vacuum-assisted closure device covered the wound [11]. Unfortunately, in one case, surgical excision was not performed because of left brachiocephalic vein occlusion [12]. Reconstruction is highly dependent on the extent of the defect.…”

Section: Discussionmentioning

confidence: 99%

Giant Anterior Chest Wall Basal Cell Carcinoma: An Approach to Palliative Reconstruction

Santos

Prendergast

Leis

2016

Case Reports in Oncological Medicine

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Anterior chest wall giant basal cell carcinoma (GBCC) is a rare skin malignancy that requires a multidisciplinary treatment approach. This case report demonstrates the challenges of anterior chest wall GBCC reconstruction for the purpose of palliative therapy in a 72-year-old female. Surgical resection of the lesion included the manubrium and upper four ribs. The defect was closed with bilateral pectoral advancement flaps, FlexHD, and pedicled VRAM. The palliative nature of this case made hybrid reconstruction more appropriate than rigid sternal reconstruction. In advanced metastatic cancers, the ultimate goals should be to avoid risk for infection and provide adequate coverage for the defect.

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“…Of the six described cases that we are aware of, only one was judged unsuitable for either surgery or radiotherapy on account of mediastinal infiltration and occlusion of the left brachiocephalic vein 8. All other cases were treated by surgical excision with or without neoadjuvant or adjuvant therapy.…”

Section: Discussionmentioning

confidence: 99%

Giant anterior chest wall basal cell carcinoma: a reconstructive challenge and review of the literature

2013

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SUMMARYGiant basal cell carcinomas (GBCC) are rare, accounting for <1% of BCCs. Those occurring on the anterior chest wall are a very rare subset that brings particular reconstructive challenges. We describe a 75-year-old man whose 13.5 cm diameter ulcerating GBCC on his left anterior chest came to medical attention following a fall. The lesion was resected en-bloc with adjacent ribs, and reconstructed with an omental flap, superiorly pedicled vertical rectus abdominus myocutaneous (VRAM) flap and split skin grafting. While the myriad reasons for delayed presentation of giant cutaneous malignancies are well documented, the complex nature of reconstruction and requirement for an integrated multidisciplinary approach are less so. It is of importance to note that the cicatricial nature of these lesions may result in a much larger defect requiring reconstruction than appreciated prior to resection. Documented cases of anterior chest wall GBCC and the treatment strategies employed are reviewed. BACKGROUND

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Giant basal cell carcinoma of the thoracic wall: a case report and review of the literature

Cited by 36 publications

References 25 publications

Super giant basal cell carcinoma of the abdominal wall: still possible in the 21st century

Super giant basal cell carcinoma of the abdominal wall: still possible in the 21st century

Giant Anterior Chest Wall Basal Cell Carcinoma: An Approach to Palliative Reconstruction

Giant anterior chest wall basal cell carcinoma: a reconstructive challenge and review of the literature

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