Giant appendiceal mucocele as a first manifestation in a patient with silent ulcerative colitis: A case report

Abdulghaffar, Shareefa; Badrawi, Noor; Khairi, Tarig; Keloth, Tasnim; Businge, Paul Emmanuel

doi:10.1016/j.radcr.2022.01.076

Cited by 2 publications

(1 citation statement)

References 9 publications

(16 reference statements)

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“…AMNs remain a rare clinical entity in IBD patients: to this date, current evidence relies on 22 [ 18 , 19 , 21 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 46 ] case reports and only 1 retrospective case–control study [ 14 ]. To our knowledge, this is the very first review of cases of AMN in IBD patients.…”

Section: Discussionmentioning

confidence: 99%

Appendiceal Mucinous Neoplasms and Inflammatory Bowel Disease: Systematic Review of the Literature

Bonomi,

Ferrario,

Frontali

et al. 2023

JCM

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There is no clear evidence on the prevalence and clinical presentation of appendiceal mucinous neoplasm (AMN) among patients with inflammatory bowel disease (IBD), so a systematic review was performed to investigate the diagnosis, management and treatment of AMN in these patients. PubMed, Medline, Scopus and the Cochrane Library were searched for articles published up to September 2023. Twenty-three studies reporting data about 34 AMN patients were included. UC patients had a median age of 52 years and a median length of disease of 10 years; CD patients had a median age of 40.5 years and a median length of disease of 5 years. A pre-operative diagnosis was achieved in 44% of patients. Most patients were symptomatic (82.6%) and showed moderate–severe disease activity (61%). Surgical procedures were performed: laparoscopic appendectomy, ileocecal resection, right hemicolectomy and colectomy/proctocolectomy. Of the patients, 73.5% were diagnosed with low-grade mucinous neoplasm (LAMN) and nine with adenocarcinoma. Synchronous colorectal dysplasia/carcinoma was present in 23.5% of patients. IBD patients with long-standing disease should be routinely screened, not only for colorectal cancer but also for AMN, during gastro-enterologic follow-up. Laparoscopic appendectomy of unruptured LAMN as well as right hemicolectomy of non-metastatic adenocarcinoma are safe procedures in IBD patients.

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