Giant aneurysm of the non-coronary sinus of Valsalva

Treacher Collins Syndrome

“…3,4 The specific causes of sinus of Valsalva aneurysms have been difficult to determine, but studies have suggested both an acquired and congenital origin. Acquired sinus of Valsalva aneurysms are typically caused by parenchymal degeneration associated with syphilis, infection, atherosclerosis, or cystic medial necrosis.…”