Giant Acquired Digital Fibrokeratoma Occurring on the Left Great Toe

Acquired Digital Fibrokeratoma

“…2 Other conditions to be considered in the differential diagnosis are neurofibroma, supernumerary digit, cutaneous horn, and verruca vulgaris. 4,6 Histopathology of the lesions described by Kint et al 2 when they examined 50 cases of acquired digital fibrokeratoma showed 3 variants. The first type contained a core of thick, densely packed collagen bundles with a hyperkeratotic epidermis.…”

“…3 They do not spontaneously resolve and are located predominantly on the fingers and toes. 2,4 Reports of nail involvement of an acquired digital fibrokeratoma are rare. 5 Hashiro et al 5 describe 1 case arising from the nail bed near the nail matrix.…”

“…3 These lesions are usually 3 to 5 mm. 4 They can have an appearance of a rudimentary supernumerary digit or be misdiagnosed as a more common condition. 1 The lesions, when hyperkeratotic, can be mistaken for cutaneous horns.…”

Acquired digital fibrokeratoma: A case report and review of the literature

“…Typically, ADFKs are small and less than 1 cm in diameter. Ali et al and Choi et al reported 3.0 × 1.6 × 1.2-cm and 2.5 × 1.6 × 1.4-cm ADFKs on the toe, respectively, and designated them as giant ADFKs [11,13] . Frydman et al reported a 4.0 × 1.5-cm ADFK on a left foot [12] .…”

Benign Subungual Tumors

“…25 The term "acquired periungual fibrokeratoma" has been used to describe such lesions. 26,27 Clinically and histologically, fibrokeratomas are identical to Koenen tumors. Because ungual fibromas may be the only cutaneous manifestation of tuberous sclerosis in some patients, 28,29 their presence warrants clinical and genetic evaluation.…”