Gianotti-Crosti syndrome

Brandt, Oliver; Abeck, Dietrich; Gianotti, Raffaele; Burgdorf, Walter H. C.

doi:10.1016/j.jaad.2005.09.033

Cited by 128 publications

(146 citation statements)

References 60 publications

Supporting

Mentioning

133

Contrasting

Unclassified

Order By: Relevance

“…10 A distribution similar to Gianotti-Crosti was documented in one-third of the patients in our study, with lesions involving the cheeks, extensor surfaces of the extremities, and buttocks, but sparing the trunk. 30 Classic GianottiCrosti is characterized by monomorphous lichenoid papules and/or papulovesicles, whereas the eruption associated with this outbreak was more often papulovesicular with prominent erosions. Epstein-Barr virus and hepatitis B virus are the most commonly reported causes of GianottiCrosti, 30 but enteroviruses such as coxsackieviruses A16, B4, and B5 have also been implicated.…”

Section: Figurementioning

confidence: 99%

“…30 Classic GianottiCrosti is characterized by monomorphous lichenoid papules and/or papulovesicles, whereas the eruption associated with this outbreak was more often papulovesicular with prominent erosions. Epstein-Barr virus and hepatitis B virus are the most commonly reported causes of GianottiCrosti, 30 but enteroviruses such as coxsackieviruses A16, B4, and B5 have also been implicated. 31 A petechial and purpuric rash was documented in 17% of our patients, most often in those aged .5 years and most frequently found on acral sites.…”

Section: Figurementioning

confidence: 99%

See 1 more Smart Citation

“Eczema Coxsackium” and Unusual Cutaneous Findings in an Enterovirus Outbreak

Oza²,

et al. 2013

View full text Add to dashboard Cite

OBJECTIVE: To characterize the atypical cutaneous presentations in the coxsackievirus A6 (CVA6)–associated North American enterovirus outbreak of 2011–2012. METHODS: We performed a retrospective case series of pediatric patients who presented with atypical cases of hand, foot, and mouth disease (HFMD) from July 2011 to June 2012 at 7 academic pediatric dermatology centers. Patients were included if they tested positive for CVA6 or if they met clinical criteria for atypical HFMD (an enanthem or exanthem characteristic of HFMD with unusual morphology or extent of cutaneous findings). We collected demographic, epidemiologic, and clinical data including history of skin conditions, morphology and extent of exanthem, systemic symptoms, and diagnostic test results. RESULTS: Eighty patients were included in this study (median age 1.5 years, range 4 months–16 years). Seventeen patients were CVA6-positive, and 63 met clinical inclusion criteria. Ninety-nine percent of patients exhibited a vesiculobullous and erosive eruption; 61% of patients had rash involving >10% body surface area. The exanthem had a perioral, extremity, and truncal distribution in addition to involving classic HFMD areas such as palms, soles, and buttocks. In 55% of patients, the eruption was accentuated in areas of eczematous dermatitis, termed “eczema coxsackium.” Other morphologies included Gianotti-Crosti–like (37%), petechial/purpuric (17%) eruptions, and delayed onychomadesis and palm and sole desquamation. There were no patients with serious systemic complications. CONCLUSIONS: The CVA6-associated enterovirus outbreak was responsible for an exanthem potentially more widespread, severe, and varied than classic HFMD that could be confused with bullous impetigo, eczema herpeticum, vasculitis, and primary immunobullous disease.

show abstract

Section: Figurementioning

confidence: 99%

Section: Figurementioning

confidence: 99%

“Eczema Coxsackium” and Unusual Cutaneous Findings in an Enterovirus Outbreak

Oza²,

et al. 2013

View full text Add to dashboard Cite

show abstract

“…Gianotti-Crosti syndrome (GCS) [54], also termed 'papular acrodermatitis of childhood', is a peculiar, self-limited and largely asymptomatic skin eruption featuring almost monomorphous papular or papulovesicular lesions located mainly on the face and distal aspects of the four limbs ( Figure 16). Mucosal involvement is never described.…”

Section: Gianotti-crosti Syndromementioning

confidence: 99%

“…Current views on the issue span from a role of immune complex deposition to occurrence of virus-related delayed hypersensitivity reactions. Furthermore, an association between immunization and GCS has long been outlined, with anti-HBV and anti-HAV vaccinations being included in the list of triggering factors [54][55][56][57].…”

Section: Gianotti-crosti Syndromementioning

confidence: 99%

The Skin and Viral Liver Disease

Mastrolonardo¹

2013

Practical Management of Chronic Viral Hepatitis

View full text Add to dashboard Cite

“…2 Following the tradition of the times, Crosti's name was listed as first author, but today this entity is universally known as Gianotti-Crosti syndrome. 3 Dr…”

mentioning

confidence: 99%