Ghrelin and depressive symptoms in patients with first‐episode drug‐naïve major depressive disorder: The mediating role of hypothalamic‐pituitary‐adrenal axis
Chuhao Zhang,
Yeqing Dong,
ShuHua Li
et al.
Abstract:BackgroundMajor depressive disorder (MDD) is one of the global burdens of disease, and its pathogenesis remains unclear. An increasing amount of research indicates that ghrelin regulates mood in patients with MDD. Still, current results are inconsistent, and the mechanisms underlying how ghrelin modulates depressive symptoms are inconclusive, especially in first‐episode drug‐naïve MDD patients. Therefore, this study aims to investigate the relationship and potential mechanism between ghrelin and first‐episode … Show more
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