Ghost Cell Tumors

A multicentre study of 268 cases of calcifying odontogenic cysts and a literature review

“…Considering the low recurrence risk, another approach is conservative treatment with local excision. However, long‐term follow‐up is recommended (Emam et al., ; Kim et al., ; Sheikh et al., ; Souza et al., ). Our study consisted of 182 excisional biopsy samples of COC, obtained from different services across Brazil.…”

“…Because of the potential for growth, displacement of associated teeth and root resorption, marsupialization or decompression is indicated for extensive lesions (Fregnani et al, 2003;Li & Yu, 2003;Sheikh, Cohen, Ramer, & Payami, 2017). Considering the low recurrence risk, another approach is conservative treatment with local excision.…”

“…However, long-term follow-up is recommended (Emam et al, 2017;Kim et al, 2016;Sheikh et al, 2017;Souza et al, 2007). Our study consisted of 182 excisional biopsy samples of COC, obtained from different services across Brazil.…”

Calcifying Odontogenic Cyst with Extensive Areas of Dentinoid: Uncommon Case Report and Update of Main Findings

“…Radiographically, these lesions are usually an unilocular, well-defined radiolucency, although the lesion occasionally may appear multilocular. Radiopaque structures within the lesion, either irregular calcifications or tooth-like densities, may also be present in some cases [ 8 – 11 ].…”

“…The distinct feature of COC is a cystic lining demonstrating “ghost” epithelial cells with a propensity to calcify. This cyst most commonly occurs as a well-defined cystic lesion with a fibrous capsule and a lining of odontogenic epithelium with Ameloblastomatous appearance [ 10 , 11 ]. Areas of an eosinophilic matrix material that are considered by some authors to represent dentinoid also may be present adjacent to the epithelial component.…”