GH therapy in children with juvenile idiopathic arthritis: a four-decade review
Giulia Sassano,
Saverio La Bella,
Armando Di Ludovico
et al.
Abstract:.
Chronic inflammatory conditions, such as juvenile idiopathic arthritis, are associated
with growth failure. Growth failure appears to be correlated with both the effects of
inflammation and negative effects of glucocorticoids (used as therapeutic option) on the
growth hormone axis and locally on the growth plate and bone metabolism. In the last
decade, the introduction of biologics has changed the disease course regarding
consequences and outcomes. Anyway in some cases, treatment with biologics ha… Show more
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