GFR and Cardiovascular Outcomes After Acute Myocardial Infarction: Results From the Korea Acute Myocardial Infarction Registry

Bae, Eun Hui; Lim, Sang Yup; Cho, Kyung Hoon; Choi, Joon Seok; Kim, Chang Seong; Park, Jeong Woo; Kwon, Seong; Jeong, Myung Ho; Kim, Soo Wan

doi:10.1053/j.ajkd.2012.01.016

Cited by 80 publications

(74 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…26) These reports are in line with our results that showed that the use of aspirin, ACE inhibitors, or ARBs and statins, during hospitalization, reduced the risk of 1-year mortality in patients with renal dysfunction. However, the use of diuretics had a deleterious effect on 1-year survival during the early stage of AMI accompanying CHF, regardless of renal dysfunction.…”

Section: Discussionsupporting

confidence: 90%

Influence of Renal Dysfunction on Clinical Outcomes in Patients With Congestive Heart Failure Complicating Acute Myocardial Infarction

Kim

Kang

et al. 2013

Int. Heart J.

Self Cite

View full text Add to dashboard Cite

SummaryThe clinical course and medical treatment of patients with congestive heart failure (CHF) complicating acute myocardial infarction (AMI) are not well established, especially in patients with concomitant renal dysfunction. We performed a retrospective analysis of the prospective Korean Acute Myocardial Infarction Registry to assess the medical treatments and clinical outcomes of patients with CHF (Killip classes II or III) complicated by AMI, in the presence or absence of renal dysfunction. Of 13,498 patients with AMI, 2769 (20.5%) had CHF on admission. Compared to CHF patients with preserved renal function, in-hospital mortality and major adverse cardiac events were increased both at 1 month and at 1 year after discharge in patients with renal dysfunction (1154; 41.7%). Postdischarge use of aspirin, betablockers, calcium channel blockers, angiotensin-converting enzyme inhibitors, or angiotensin II receptor blockers and statins significantly reduced the 1-year mortality rate for CHF patients with renal dysfunction; such reduction was not observed for those without renal dysfunction, except in the case of aspirin. Patients with CHF complicating AMI, which is accompanied by renal dysfunction, are at higher risk for adverse cardiovascular outcomes than patients without renal dysfunction. However, they receive fewer medications proven to reduce mortality rates. (Int Heart J 2013; 54: 304-310) Key words: Major adverse cardiac events P atients with acute myocardial infarctions (AMIs) frequently show evidence of congestive heart failure (CHF) and have a high risk of morbidity and mortality. These patients have a 3-to 4-fold increased risk of in-hospital mortality and have longer hospital stays than patients with AMIs but no signs of heart failure.

show abstract

Section: Discussionsupporting

confidence: 90%

Influence of Renal Dysfunction on Clinical Outcomes in Patients With Congestive Heart Failure Complicating Acute Myocardial Infarction

Kim

Kang

et al. 2013

Int. Heart J.

Self Cite

View full text Add to dashboard Cite

show abstract

“…The KAMIR is a Korean prospective, open, observational, multi-center online registry investigating the risk factors of mortality in MI patients since November 2005. Details of the KAMIR have been published elsewhere [2,13]. We assessed a cohort of 8,063 consecutive patients who were admitted to the hospital between November 1, 2005, and July 31, 2008, and had a discharge diagnosis of STEMI, confirmed by both cardiac enzyme and electrocardiographic analyses.…”

Section: Korea Acute Myocardial Infarction Registrymentioning

confidence: 99%

“…Impaired renal function is a well-known independent risk factor for mortality and morbidity in patients with myocardial infarction (MI) [1,2]. Several studies reported that impaired renal function is more prevalent in women, while female MI patients are generally older and have more comorbidity than male patients [2,3].…”

Section: Introductionmentioning

confidence: 99%

“…Several studies reported that impaired renal function is more prevalent in women, while female MI patients are generally older and have more comorbidity than male patients [2,3]. The impact of gender difference on prognosis after ST-segment elevated MI (STEMI) has been a popular and debated topic in clinical practice [4][5][6][7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Does gender influence the impact of impaired renal function on prognosis after ST-segment elevated myocardial infarction?

Choi

Kim²,

Kang³

et al. 2013

Cardiol J

Self Cite

View full text Add to dashboard Cite

show abstract

“…133,134 Based on estimated glomerular filtration rate (eGFR), previous studies have shown a powerful relationship between the severity of CKD and poor outcomes in ACS and STEMI patients. [135][136][137][138][139][140][141] Multiple possible mechanisms for the cardio-renal syndrome, the strong association between CKD and increased risk for death and cardiovascular disease, exist. A high prevalence of known risk factors for cardiovascular disease and death such as DM, HT and heart failure is observed in patients with CKD.…”

Section: Chronic Kidney Disease In Patients With Acsmentioning

confidence: 99%

Improving management of STEMI patients treated with primary PCI: Pharmacotherapy, renal function estimation and gender perspective

Venetsanos¹

View full text Add to dashboard Cite

GFR and Cardiovascular Outcomes After Acute Myocardial Infarction: Results From the Korea Acute Myocardial Infarction Registry

Cited by 80 publications

References 26 publications

Influence of Renal Dysfunction on Clinical Outcomes in Patients With Congestive Heart Failure Complicating Acute Myocardial Infarction

Influence of Renal Dysfunction on Clinical Outcomes in Patients With Congestive Heart Failure Complicating Acute Myocardial Infarction

Does gender influence the impact of impaired renal function on prognosis after ST-segment elevated myocardial infarction?

Improving management of STEMI patients treated with primary PCI: Pharmacotherapy, renal function estimation and gender perspective

Contact Info

Product

Resources

About