GFP-labeled Schwann cell-like cells derived from hair follicle epidermal neural crest stem cells promote the acellular nerve allografts to repair facial nerve defects in rats

Engineering cell-derived extracellular matrix for peripheral nerve regeneration

“…In the field of peripheral nerve tissue engineering, acellular allogeneic nerves are typical td-ECM scaffolds. They preserve the native heterogeneous composition and inherent ultrastructure, therefore possessing tissue-specific functionality to some extent [ 24 , 25 ]. Acellular nerve grafts have been widely selected in the treatment of PNI and there are commercially available finished products that have been approved [ 26 , 27 ].…”