Gezielte Entfernung axillärer Lymphknoten nach Kohlenstoffmarkierung bei Patientinnen mit primär systemisch behandeltem Mammakarzinom

Hartmann, Steffi; Stachs, Angrit; Kühn, Thorsten; Boniface, Jana de; Banys‐Paluchowski, Maggie; Reimer, Toralf

doi:10.1055/a-1782-3342

Cited by 1 publication

(1 citation statement)

References 24 publications

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“…The TAD is a combination of SLNB and targeted lymph node biopsy (TLNB), that is, the removal of a biopsied and clipped metastatic lymph node. This surgical technique can further reduce the FNR in initially cNþ patients undergoing NACT to an acceptable level of 1.4% [27] -9.1% [28]. Interestingly, the SN and TLN represent the same lymph node in up to 70% of patients [29].…”

Section: Controversies In the Cnr Settingmentioning

confidence: 99%

Controversies in axillary management of patients with breast cancer – updates for 2024

Tauber,

Bjelic-Radisic,

Thill

et al. 2023

Current Opinion in Obstetrics &Amp; Gynecology

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Purpose of review For some time now, the question of de-escalation in axillary staging in breast cancer patients has been raised. The aim is to improve the patients’ quality of life and reduce morbidity by optimizing surgical strategies with a high level of oncological safety. This review offers a current overview of published evidence and clinical practice, aiming to guide the surgical community as they reassess and reshape their practices. Recent findings Years after introducing sentinel lymph node biopsy (SLNB) in clinically node negative breast cancer patients several guidelines suggest completely omitting SLNB in older patients with low-risk tumors. It is worth noting that for patients with a metastatic sentinel lymph node in the upfront surgery setting, a de-escalation of axillary surgery may in fact lead to an escalation of radiation therapy. Currently, there is limited evidence on the axillary surgical approach for patients with initially positive node status achieving complete axillary response (ycN0), resulting in heterogenous guideline recommendations. Summary Innovative trials are contributing to a growing evidence on de-escalation of axillary surgery with the aim of reducing arm morbidity and improving long-term health-related quality of life.

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Section: Controversies In the Cnr Settingmentioning

confidence: 99%