Abstract:Published by Lippincott Williams & WilkinsL ower extremity artery disease (LEAD) is a disease of the lower extremities caused by narrowing and/or blockage of arteries in the lower extremity resulting in decreased blood flow. This decrease in blood flow leads to reduced transportation of oxygen and essential nutrients to the limbs. 1 As a result, patients may experience pain, numbness, infection, and, in cases with severe occlusion, gangrene, which often leads to amputation. 1 Lower extremity artery disease in… Show more
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