I want to thank UNICAMP and, in particular, to the entire team of the Institute of Computing and the Dean of Graduate Studies for the opportunity to develop my master's degree within the Institution, which provided the environment, resources, and professors for my personal development during my master's degree.I would like to especially thank my advisor, professor Esther L. Colombini, for her tireless dedication, contribution, and support since the beginning of my master's degree. She always tried to help and guide me at all stages, even from a remote location and in different time zones, looking for alternatives and new ideas even when I seemed to be lost, reviewing, and supporting my work even in the most challenging deadlines. I am eternally grateful for her support, without which this work and the published articles would not exist.I also thank professor Dra. Maria Claudia Ferrari de Castro, for collaborating with ideas and references, for participating in my Qualification round, and above all, for sharing the Parkinson's Disease datasets from her previous work, without which this work would also not be possible.I am thankful to my Siemens co-workers in Brazil and Germany, for the opportunity to share ideas, problems and solutions, and for allowing me to dedicate myself to the master's degree simultaneously with my career activities.Finally, I would like to thank my whole family for their support and encouragement since the beginning of this journey. To my parents, for believing in me and for always being proud, even in the smallest achievements, to my wife, who during all this time faced countless challenges, such as relocating to another country, having the birth of our first child, and despite all that, still finding the time to encourage me and providing the best environment so I could focus on this work. Finally, I'm grateful to my son Erik, who has brought me a new meaning to life and inspiration every day.