Gestational gigantomastia with spontaneous resolution in an Indian woman

Abstract

We present the case of a 20-year-old woman, primigravida with 24 weeks of amenorrhoea due to pregnancy. She came with symptoms of rapidly increasing size of both the breasts since 8 weeks. On examination, both breasts were grossly enlarged, right more than left, with the level of the nipples reaching beyond the level of the umbilicus. Breast circumference was measured to be 72 cm on the right, and left breast was 66 cm. No palpable lumps in both breasts. No axillary lymphadenopathy noted. Hormonal studies were found to be within the normal range. The pregnancy was terminated due to pre-eclampsia. The patient opted for regular follow-up and observation. While regularly following up, the size of both breasts was observed to gradually reduce to a circumference of 40 cm on the right and 30 cm on the left.

The Place of Reductive Surgery in the Management of Gestational Ulcerative Gigantomastia: A Case Report at Sourô Sanou Teaching Hospital

“…Medical treatment with bromocriptine has unanimously proved to be inefficient. Spontaneous resolution has been noted in some minor cases [4, 13]. But this particular case was at the limit of a spontaneous mastectomy with a significant loss of cutaneous substance at the distal 1/3.…”

“…This is done by minimal morphological investigations, e.g., ultrasound scan or MRI of the breast, and eventually by an incisional biopsy of the lesions or fine needle aspiration biopsy guided by USS result [8]. Except local treatment to avoid superimposed infections, antalgic, and psychotherapy assistance, specific treatment of this gestational gigantomastia remains controversial [2, 3, 4, 6, 7, 13–15]. Medical treatment with bromocriptine has unanimously proved to be inefficient.…”

Gestational gigantomastia on a Saudi woman: A case report on surgical removal and reconstruction and management of complications, KFSH&RC

“…This is the reason why total mastectomy is preferred several months after delivery (when the baby can wean off breastfeeding) and reduction mammoplasty is performed weeks or months before delivery. In very rare cases, GG underwent complete resolution after pregnancy even without medical interventions [ 13 ].…”

Severe Bilateral Breast Hypertrophy in a Pregnant Patient: A Case Report

“…3 Symptoms include rapid breast tissue enlargement, pain, skin breakdown, immobility, tissue necrosis, sepsis, deep vein thrombosis, hemorrhage, mastalgia, ulceration, infection, backache, postural problems, chronic traction injury to intercostal nerves, neck and back pain, bleeding from breast ulcers, and lower limb swelling. [7][8][9][10][11] While some cases may resolve after pregnancy, most require medical or surgical intervention. 2 Medical therapies aim to avoid surgery during pregnancy and have been successful in 39% of cases.…”